Bace1

Reference Set (32 Compounds)

C[C@@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CCS(=O)(=O)CC(N)=N1 ZINC000201827394

ZINC000201827394 (search)

C[C@@H]1C(N)=N[C@](C)(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CCS1(=O)=O ZINC000201657943

ZINC000201657943 (search)

C[C@@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CCSCC(N)=N1 ZINC000201827307

ZINC000201827307 (search)

C[C@@]1(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CCSCC(N)=N1 ZINC000201827348

ZINC000201827348 (search)

C[C@@]1(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CCS(=O)(=O)CC(N)=N1 ZINC000201827435

ZINC000201827435 (search)

C[C@@H]1C(N)=N[C@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CCS1(=O)=O ZINC000201832021

ZINC000201832021 (search)

[C-]#[N+]c1ccc(C(=O)Nc2ccc(F)c([C@]3(C)CCS(=O)(=O)C(C)(C)C(=N)N3)c2)nc1 ZINC000473228753

ZINC000473228753 (search)

CC1(C)C(N)=N[C@](C)(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CCS1(=O)=O ZINC000201832173

ZINC000201832173 (search)

[C-]#[N+]c1ccc(C(=O)Nc2ccc(F)c([C@@]3(C)NC(=N)CS(=O)(=O)[C@H]4COC[C@@H]43)c2)nc1 ZINC000473228837

ZINC000473228837 (search)

C[C@H]1SCC[C@@](C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)N=C1N ZINC000201831948

ZINC000201831948 (search)

C[C@H]1SCC[C@@](C)(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)N=C1N ZINC000201827484

ZINC000201827484 (search)

[C-]#[N+]c1ccc(C(=O)Nc2ccc(F)c([C@]3(C(F)F)CCS(=O)(=O)CC(=N)N3)c2)nc1 ZINC000473228746

ZINC000473228746 (search)

C[C@@H]1C(N)=N[C@](C)(c2cc(NC(=O)c3[nH]ncc3Cl)ccc2F)CCS1(=O)=O ZINC000201832094

ZINC000201832094 (search)

CC1(C)C(N)=N[C@](C)(c2cc(NC(=O)c3[nH]ncc3Cl)ccc2F)CCS1(=O)=O ZINC000201832221

ZINC000201832221 (search)

CC#Cc1cncc(-c2cccc([C@@]3(c4cc(C)c(=O)n(CC)c4)N=C(N)c4c(F)cccc43)c2)c1 ZINC000095574104

ZINC000095574104 (search)

CCn1cc([C@]2(c3cccc(C#CC4CC4)c3)N=C(N)c3c(F)cccc32)cc(C)c1=O ZINC000095579272

ZINC000095579272 (search)

COc1cnc(C(=O)Nc2ccc(F)c([C@]3(C)COCC(=N)N3)c2)cn1 ZINC000473152394

ZINC000473152394 (search)

C[C@@]1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)COCC(N)=N1 ZINC000068248416

ZINC000068248416 (search)

C[C@@]1(c2cccc(NC(=O)c3ccc(Cl)cn3)c2)COCC(N)=N1 ZINC000068248417

ZINC000068248417 (search)

Cc1cc([C@@]2(c3cccc(-c4cncnc4)c3)N=C(N)c3c(F)cccc32)cn(C)c1=O ZINC000095577643

ZINC000095577643 (search)

COc1c(C)cc([C@@]2(c3cccc(-c4cncnc4)c3)N=C(N)c3c(F)cccc32)nc1C ZINC000068205982

ZINC000068205982 (search)

NC1=N[C@@](c2cccc(-c3cncnc3)c2)(c2ccnc(C(F)F)c2)c2cccc(F)c21 ZINC000068205977

ZINC000068205977 (search)

NC1=N[C@@](c2cccc(-c3cncnc3)c2)(c2ccnc(C(F)F)c2)c2cc(F)cc(F)c21 ZINC000095573460

ZINC000095573460 (search)

NC1=N[C@](c2ccncc2)(c2cccc(-c3cncnc3)c2)c2cccc(F)c21 ZINC000095577655

ZINC000095577655 (search)

NC1=N[C@](c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncnc3)c2)c2cccc(F)c21 ZINC000095572727

ZINC000095572727 (search)

NC1=N[C@@](c2cccc(-c3cncnc3)c2)(c2ccnc(C(F)(F)F)c2)c2cccc(F)c21 ZINC000095571753

ZINC000095571753 (search)

COc1cc2c(cc1OC)C(=O)/C(=C/C1CCN(Cc3ccccc3)CC1)C2 ZINC000000597028

ZINC000000597028 (search)

$COc1ccc2c(c1)C/C(=C\C1CCN(Cc3ccccc3)CC1)C2=O ZINC000137817655$

ZINC000137817655 (search)

$COc1cccc(CN2CCC(/C=C3\Cc4cc(OC)ccc4C3=O)CC2)c1 ZINC000653866602$

ZINC000653866602 (search)

O=C1/C(=C/C2CCN(Cc3ccccc3)CC2)Cc2cc3c(cc21)OCO3 ZINC000653866658

ZINC000653866658 (search)

O=C1/C(=C/C2CCN(Cc3ccccc3)CC2)Cc2cc(O)ccc21 ZINC000653876674

ZINC000653876674 (search)

O=C1/C(=C/C2CCN(Cc3ccccc3)CC2)Cc2cccc(O)c21 ZINC000653876692

ZINC000653876692 (search)