METAP1

Reference Set (125 Compounds)

CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1 ZINC000013521832

ZINC000013521832 (search)

CCCCCCCCCCCCCC(=O)O[C@H]1CC[C@H](NC(=O)[C@H](OC)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)C)C(=O)NC1 ZINC000043606333

ZINC000043606333 (search)

CC[C@@H](C)CCCCCCCCCCC(=O)O[C@H]1CC[C@H](NC(=O)[C@H](OC)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)C)C(=O)N(C)C1 ZINC000070631564

ZINC000070631564 (search)

CCCC[C@@H](N)C(=O)CNC1CC1 ZINC000013559615

ZINC000013559615 (search)

CCSCC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12 ZINC000012504145

ZINC000012504145 (search)

CCSCC[C@@H](N)[C@H](O)C(=O)NOc1ccccc1 ZINC000027895067

ZINC000027895067 (search)

CCSCC[C@@H](N)[C@H](O)C(=O)NNc1ccc(C)cc1 ZINC000027902906

ZINC000027902906 (search)

CC(C)CSC[C@@H](N)[C@H](O)C(=O)NOc1ccccc1 ZINC000027993864

ZINC000027993864 (search)

CCCSC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12 ZINC000027979387

ZINC000027979387 (search)

CCCSC[C@@H](N)[C@H](O)C(=O)NOc1ccccc1 ZINC000027996209

ZINC000027996209 (search)

CC(C)CSC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12 ZINC000014964989

ZINC000014964989 (search)

CC(C)SCC[C@@H](N)[C@H](O)C(=O)NOc1ccccc1 ZINC000027985447

ZINC000027985447 (search)

CCCSC[C@@H](N)[C@H](O)C(=O)NNc1ccc(C)cc1 ZINC000027903614

ZINC000027903614 (search)

C[C@@H](NC(=O)[C@@H](O)[C@H](N)CC1CCCCC1)c1ccc2ccccc2c1 ZINC000027986510

ZINC000027986510 (search)

Cc1ccc(NNC(=O)[C@@H](O)[C@H](N)CSCC(C)C)cc1 ZINC000027979922

ZINC000027979922 (search)

CC(C)CSC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1 ZINC000014965002

ZINC000014965002 (search)

CCSCC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1 ZINC000014964998

ZINC000014964998 (search)

CCSCC[C@@H](N)[C@H](O)C(=O)NNc1cccc2ccccc12 ZINC000027987972

ZINC000027987972 (search)

CN(C)c1ccc(/C=C/C=C2C(=O)NC(=O)NC2=O)cc1 ZINC000000179359

ZINC000000179359 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271229

ZINC000096271229 (search)

c1ccc(-c2nc(N3CCOCC3)c3ccccc3n2)nc1 ZINC000000521854

ZINC000000521854 (search)

Cc1nc(-c2ccc(F)cn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271230

ZINC000096271230 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@@H](CCc2ccccc2)c2ccccc2)c1Cl ZINC000096271202

ZINC000096271202 (search)

C[C@H](O)c1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269552

ZINC000096269552 (search)

O=Cc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269560

ZINC000096269560 (search)

CC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(c2cc(-c3ccccn3)nc3ccccc23)CC1 ZINC000096269547

ZINC000096269547 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NC(=O)CCc2ccccc2)c2ccccc2)c1Cl ZINC000096271221

ZINC000096271221 (search)

CCOC(=O)c1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269554

ZINC000096269554 (search)

Oc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269558

ZINC000096269558 (search)

COc1ccc(N2CCN(c3nc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000095921329

ZINC000095921329 (search)

COc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269562

ZINC000096269562 (search)

c1ccc(-c2nc(N3CCCCC3)c3ccccc3n2)nc1 ZINC000000529784

ZINC000000529784 (search)

O=[N+]([O-])c1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269559

ZINC000096269559 (search)

CC(=O)Nc1ncc(CC(=O)N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)s1 ZINC000096269548

ZINC000096269548 (search)

c1ccc(-c2nc(NCCc3[nH]cc4ccccc34)c3ccccc3n2)nc1 ZINC000096269551

ZINC000096269551 (search)

Cc1nc(-c2ccc(N(C)C)cn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271226

ZINC000096271226 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@@H](CCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271200

ZINC000096271200 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NC(=O)CCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271220

ZINC000096271220 (search)

CCOC(=O)COc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269556

ZINC000096269556 (search)

Cc1nc(-c2ccccn2)nc(NCCc2ccccc2)c1Cl ZINC000000108774

ZINC000000108774 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@@H](CCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271198

ZINC000096271198 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271214

ZINC000096271214 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCc2ccccc2)c2ccccc2)c1Cl ZINC000096271217

ZINC000096271217 (search)

Cc1ccc(S(=O)(=O)N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269566

ZINC000096269566 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271215

ZINC000096271215 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271216

ZINC000096271216 (search)

COc1ccc(-c2nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN3CCNCC3)c3ccccc3)n2)nc1 ZINC000096271231

ZINC000096271231 (search)

Cc1nc(-c2ccccn2)nc(NCCNc2ccc(C(F)(F)F)cn2)c1Cl ZINC000024817407

ZINC000024817407 (search)

Cc1nc(-c2ccc([N+](=O)[O-])cn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271227

ZINC000096271227 (search)

c1ccc(-c2ccccn2)nc1 ZINC000000105227

ZINC000000105227 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2ccco2)c2ccccc2)c1Cl ZINC000096271207

ZINC000096271207 (search)

Cc1nc(-c2ccc(Br)cn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271228

ZINC000096271228 (search)

Cc1nc(-c2ccccn2)nc(NC2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)c1Cl ZINC000020412737

ZINC000020412737 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2cccs2)c2ccccc2)c1Cl ZINC000096271206

ZINC000096271206 (search)

c1ccc(-c2cc(N3CCCCC3)c3ccccc3n2)nc1 ZINC000020432400

ZINC000020432400 (search)

Clc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1Cl ZINC000096269565

ZINC000096269565 (search)

c1ccc(-c2cc(N3CCOCC3)c3ccccc3n2)nc1 ZINC000019809797

ZINC000019809797 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2ccc(O)cc2)c2ccccc2)c1Cl ZINC000096271211

ZINC000096271211 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@@H](NCCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096269549

ZINC000096269549 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCn2cccc2)c2ccccc2)c1Cl ZINC000096271204

ZINC000096271204 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2ccc(C#N)cc2)c2ccccc2)c1Cl ZINC000096271209

ZINC000096271209 (search)

COc1ccnc(-c2nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN3CCNCC3)c3ccccc3)n2)c1 ZINC000096271224

ZINC000096271224 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2ccc(Cl)cc2)c2ccccc2)c1Cl ZINC000096271210

ZINC000096271210 (search)

C=CCOc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269561

ZINC000096269561 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NS(=O)(=O)CCN2CCN(CCO)CC2)c2ccccc2)c1Cl ZINC000096271236

ZINC000096271236 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NC(=O)CCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271243

ZINC000096271243 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NC(=O)CCCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271218

ZINC000096271218 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCc2ccc3ccccc3n2)c2ccccc2)c1Cl ZINC000096271205

ZINC000096271205 (search)

CO[C@@H](C(=O)N[C@H]1CC[C@@H](OC(=O)C2CCCCC2)CNC1=O)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)(C)C ZINC000003975718

ZINC000003975718 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NC(=O)Cc2ccccc2)c2ccccc2)c1Cl ZINC000096271222

ZINC000096271222 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271212

ZINC000096271212 (search)

Cc1nc(-c2cc(Cl)ccn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271223

ZINC000096271223 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NCCCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271213

ZINC000096271213 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NS(=O)(=O)CCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271237

ZINC000096271237 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NCCCCN2CCN(CCO)CC2)c2ccccc2)c1Cl ZINC000096271238

ZINC000096271238 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NC(=O)CCN2CCN(CCO)CC2)c2ccccc2)c1Cl ZINC000096271245

ZINC000096271245 (search)

COc1ccc(N2CCN(c3cc(-c4ccc(Cl)cn4)nc4ccccc34)CC2)cc1 ZINC000096269563

ZINC000096269563 (search)

CN1CCN(c2cc(-c3ccccn3)nc3ccccc23)CC1 ZINC000019908879

ZINC000019908879 (search)

O=C(O)c1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269555

ZINC000096269555 (search)

c1ccc(CCNc2nc(-c3ccccn3)nc3ccccc23)cc1 ZINC000000532702

ZINC000000532702 (search)

C=C1Cc2cc(Cl)ccc2C1=O ZINC000299820893

ZINC000299820893 (search)

Cc1nc(-c2ccccn2)nc(NCCNc2cccc(C(F)(F)F)n2)c1Cl ZINC000020458540

ZINC000020458540 (search)

CN(C)c1ccc(/C=C/C=C2C(=O)NC(=S)NC2=O)cc1 ZINC000005549590

ZINC000005549590 (search)

Cc1nc(-c2ccccn2)nc(N2CCN(CCO)CC2)c1Cl ZINC000019924596

ZINC000019924596 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271242

ZINC000096271242 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NC(=O)CCCN2CCN(CCO)CC2)c2ccccc2)c1Cl ZINC000096271244

ZINC000096271244 (search)

CCCOc1ccc(CCCCN[C@@H](CNc2nc(-c3ccc(Cl)cn3)nc(C)c2Cl)c2ccccc2)cc1 ZINC000096271208

ZINC000096271208 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@H](NC(=O)CCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271219

ZINC000096271219 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NCCCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271239

ZINC000096271239 (search)

COc1ccc(N2CCN(c3cc(-c4ccc(Br)cn4)nc4ccccc34)CC2)cc1 ZINC000096269564

ZINC000096269564 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NCCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271241

ZINC000096271241 (search)

Cc1nc(-c2ccccn2)nc(N(C)Cc2ccccc2)c1Cl ZINC000000108766

ZINC000000108766 (search)

Clc1nc(-c2ccccn2)nc2ccccc12 ZINC000000522072

ZINC000000522072 (search)

c1ccc(NCCNc2nc(-c3ccccn3)nc3ccccc23)cc1 ZINC000096269550

ZINC000096269550 (search)

Cc1nc(-c2ccc(N3CCCC3)cn2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271225

ZINC000096271225 (search)

Cc1nc(-c2ccccn2)nc(NC[C@H](NCCCN2CCN(CCO)CC2)c2ccccc2)c1Cl ZINC000096271240

ZINC000096271240 (search)

O=C1NC(=O)C(=Cc2ccc(F)cc2)C(=O)N1 ZINC000002819839

ZINC000002819839 (search)

O=C1NC(=O)C(=Cc2cccc([N+](=O)[O-])c2)C(=O)N1 ZINC000003157622

ZINC000003157622 (search)

COc1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 ZINC000003896836

ZINC000003896836 (search)

Cc1nc(-c2ccc(Cl)cn2)nc(NC[C@@H](CCCCCc2ccccc2)c2ccccc2)c1Cl ZINC000096271196

ZINC000096271196 (search)

COc1cccnc1-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1 ZINC000096271233

ZINC000096271233 (search)

CO[C@@H](C(=O)N[C@H]1CC[C@H](OC(=O)CCCCCCCCCCC(C)C)CNC1=O)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)C ZINC000140931897

ZINC000140931897 (search)

C=C1Cc2cc(Br)ccc2C1=O ZINC000034557314

ZINC000034557314 (search)

CN(C)C[C@H]1Cc2cc(Br)ccc2C1=O ZINC000299820536

ZINC000299820536 (search)

CO[C@@H](C(=O)NCC(N)=O)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)(C)C ZINC000066156877

ZINC000066156877 (search)

c1ccc(CSc2nnc(Nc3ccccc3)[nH]2)cc1 ZINC000000008998

ZINC000000008998 (search)

Cc1nc(-c2ccccn2)nc(NCCc2ccccc2)c1F ZINC000096271248

ZINC000096271248 (search)

CCCC(CCC)[C@@H](N)P(=O)(O)O ZINC000035962598

ZINC000035962598 (search)

O=C1NC(=O)C(=Cc2ccc(C(=O)O)cc2)C(=O)N1 ZINC000003066698

ZINC000003066698 (search)

CO[C@@H](C(=O)NCC[C@@H](c1ccccc1)c1ccco1)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)(C)C ZINC000095576253

ZINC000095576253 (search)

CO[C@@H](C(=O)NC1Cc2ccccc2C1)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)(C)C ZINC000066166121

ZINC000066166121 (search)

O=C(O)COc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 ZINC000096269557

ZINC000096269557 (search)

O=C1NC(=S)NC(=O)C1=Cc1ccc(F)cc1 ZINC000001575001

ZINC000001575001 (search)

Cc1nc(-c2cccc(Cl)n2)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271234

ZINC000096271234 (search)

CO[C@@H](C(=O)NC[C@@H]1CCCN(C(=O)C2CC2)C1)[C@H](O)[C@@H](O)[C@H](O)/C=C/C(C)(C)C ZINC000066166119

ZINC000066166119 (search)

Cc1nc(-c2ncccc2Cl)nc(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)c1Cl ZINC000096271232

ZINC000096271232 (search)

O=C1NC(=O)C(=Cc2ccc([N+](=O)[O-])cc2)C(=O)N1 ZINC000009329507

ZINC000009329507 (search)

O=C(Nc1nccs1)c1ccccn1 ZINC000000777985

ZINC000000777985 (search)

CNc1nc(-c2ccccn2)nc(C)c1Cl ZINC000000108761

ZINC000000108761 (search)

O=C1NC(=O)C(=C/C=C/c2ccccc2)C(=O)N1 ZINC000009045952

ZINC000009045952 (search)

N[C@H](CCC1CCCCC1)P(=O)(O)O ZINC000035962734

ZINC000035962734 (search)

Cc1nc(-c2ccccn2)nc(SCCc2ccccc2)c1Cl ZINC000096271246

ZINC000096271246 (search)

CN(C)c1ccc(C=C2C(=O)NC(=O)NC2=O)cc1 ZINC000008969139

ZINC000008969139 (search)

O=C1NC(=O)C(=Cc2ccc(O)cc2)C(=O)N1 ZINC000008995178

ZINC000008995178 (search)

Cc1ccc(-c2cn[nH]n2)cc1 ZINC000013671868

ZINC000013671868 (search)