PDE4C

Reference Set (97 Compounds)

CC(C)C(=O)c1c(C(C)C)nn2ccccc12 ZINC000000004234

ZINC000000004234 (search)

COc1ccc([C@@H]2CNC(=O)C2)cc1OC1CCCC1 ZINC000000004982

ZINC000000004982 (search)

COc1ccc(C2=NO[C@H](C(=O)NO)C2)cc1OC1CCCC1 ZINC000000006384

ZINC000000006384 (search)

COc1ccc(C2=NO[C@](C)(C(=O)NO)C2)cc1OC1CCCC1 ZINC000000020039

ZINC000000020039 (search)

CCc1nn(C2CCCC2)c2c1CCn1c-2nnc1C(C)(C)C ZINC000000021913

ZINC000000021913 (search)

COc1ccc(C(=O)NCC(=O)NO)cc1OC1CCCC1 ZINC000000022075

ZINC000000022075 (search)

COc1ccc(C(=O)N[C@H](C)C(=O)NO)cc1OC1CCCC1 ZINC000000022076

ZINC000000022076 (search)

O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc(Cl)c3)n2)cc1 ZINC000000587602

ZINC000000587602 (search)

COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OC1CCCC1 ZINC000000598965

ZINC000000598965 (search)

COc1ccc([C@H](Cc2ccncc2)c2ccccc2)cc1OC1CCCC1 ZINC000000599006

ZINC000000599006 (search)

O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc([N+](=O)[O-])c3)n2)cc1 ZINC000000602427

ZINC000000602427 (search)

O=C(O)c1ccc(-c2cc3cccnc3c(-c3ccc4nonc4c3)n2)cc1 ZINC000000603119

ZINC000000603119 (search)

Clc1ncnc2ccccc12 ZINC000000809020

ZINC000000809020 (search)

CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3Cl)nnc1-2 ZINC000000840571

ZINC000000840571 (search)

[O-][n+]1cccc(C[C@@H](c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1 ZINC000001553121

ZINC000001553121 (search)

CC(C)c1cc(-c2cccc([C@H](Cc3ccncc3)c3ccc(Cl)cc3)c2)c2ncccc2c1 ZINC000001554122

ZINC000001554122 (search)

NC(=O)c1noc([C@H](CCCC2CCCCC2)CC(=O)NO)n1 ZINC000003818556

ZINC000003818556 (search)

Cc1noc(/C(=C/c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 ZINC000003964061

ZINC000003964061 (search)

C[C@@H](c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1ccc(F)cc1)c1ccc(S(C)(=O)=O)cc1 ZINC000003979798

ZINC000003979798 (search)

O=[N+]([O-])c1cccc(-c2nc(-c3ccccc3)cc3cccnc23)c1 ZINC000013805266

ZINC000013805266 (search)

O=[N+]([O-])c1cccc(-c2nc(-c3cccnc3)cc3cccnc23)c1 ZINC000013805269

ZINC000013805269 (search)

C=CCc1cc2cccnc2c(-c2cccc([N+](=O)[O-])c2)n1 ZINC000013805274

ZINC000013805274 (search)

N#Cc1cccc(-c2nc(-c3ccc(C(=O)O)cc3)cc3cccnc23)c1 ZINC000013805276

ZINC000013805276 (search)

COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OC)c2)CS3)c1 ZINC000013828709

ZINC000013828709 (search)

COc1ccc(OC)c(-c2nnc3ccc(-c4ccc(OC)c(O[C@@H]5CCOC5)c4)nn23)c1 ZINC000013831582

ZINC000013831582 (search)

Cc1ccc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)nc1 ZINC000028529186

ZINC000028529186 (search)

$CC(C)c1cc(-c2cccc(/C=C(\c3ccc(S(C)(=O)=O)cc3)c3nccs3)c2)c2ncccc2c1 ZINC000028529343$

ZINC000028529343 (search)

O=S(=O)(Nc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1)c1ccccc1 ZINC000028529386

ZINC000028529386 (search)

$C[C@@H](c1cc(-c2cccc(/C=C(\c3ccc(S(C)(=O)=O)cc3)c3ncc(C(C)(C)O)s3)c2)c2ncccc2c1)S(C)(=O)=O ZINC000028529503$

ZINC000028529503 (search)

Cc1noc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccccn2)n1 ZINC000028529519

ZINC000028529519 (search)

CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000028529539

ZINC000028529539 (search)

CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)C)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000028529543

ZINC000028529543 (search)

CC(C)NC(=O)/C(=C/c1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000028529556

ZINC000028529556 (search)

$Cc1noc(/C(=C\c2cccc(-c3cc(C(C)(C)S(C)(=O)=O)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 ZINC000028529662$

ZINC000028529662 (search)

Cc1noc(/C(=C/c2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 ZINC000028529666

ZINC000028529666 (search)

CC(C)c1cc(-c2cccc(C[C@@H](c3ccncc3)C(C)(C)O)c2)c2ncccc2c1 ZINC000028529809

ZINC000028529809 (search)

COc1cccc(-c2cc(Cc3ccncc3)cc3cccnc23)c1 ZINC000028529813

ZINC000028529813 (search)

CC(C)c1cc(-c2cccc(/C=C(/c3ccc(C(C)(C)O)cc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 ZINC000028529822

ZINC000028529822 (search)

CC(C)c1cc(-c2cccc(/C=C(/C(=O)O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 ZINC000028529829

ZINC000028529829 (search)

CC(C)c1cc(-c2cccc([C@@H](Cc3cc[n+]([O-])cc3)c3ccc(Cl)cc3)c2)c2ncccc2c1 ZINC000028529946

ZINC000028529946 (search)

$CC(C)NC(=O)/C(=C\c1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000028530105$

ZINC000028530105 (search)

C[C@@H](NC(=O)c1cccnc1Oc1ccc(F)cc1)c1cccs1 ZINC000028570798

ZINC000028570798 (search)

CCc1nn(C2CCCC2)c2c1CCn1c(-c3cccnc3)nnc1-2 ZINC000034556927

ZINC000034556927 (search)

CCc1nn(C2CCCC2)c2c1CCn1c(-c3cccc(OC)c3)nnc1-2 ZINC000035090994

ZINC000035090994 (search)

CC(=O)Nc1cc(-c2c(-c3ccc(F)cc3)nc([S@+](C)[O-])n2C)ccn1 ZINC000035983048

ZINC000035983048 (search)

N#Cc1cccc(-c2nc(OS(=O)(=O)C(F)(F)F)cc3cccnc23)c1 ZINC000036268760

ZINC000036268760 (search)

O=[N+]([O-])c1cccc(-c2nc(OS(=O)(=O)C(F)(F)F)cc3cccnc23)c1 ZINC000036268763

ZINC000036268763 (search)

O=S(=O)(Oc1cc2cccnc2c(-c2cccc(Cl)c2)n1)C(F)(F)F ZINC000036268766

ZINC000036268766 (search)

[O-][n+]1cccc(C[C@H](c2ccc(OC(F)F)c(OC3CC3)c2)c2cnc(C(O)(C(F)(F)F)C(F)(F)F)s2)c1 ZINC000036268775

ZINC000036268775 (search)

CC(=O)N(c1ccc(S(C)(=O)=O)cc1)[C@@H](C)c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 ZINC000036268779

ZINC000036268779 (search)

C[C@@H](c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1cccnc1)c1ccc(S(C)(=O)=O)cc1 ZINC000036268786

ZINC000036268786 (search)

CC(C)(c1cc(-c2cccc(C(=O)Nc3ccncc3)c2)c2ncccc2c1)S(C)(=O)=O ZINC000036268792

ZINC000036268792 (search)

Cc1cc(C(=O)N(Cc2cccc(-c3cc(C(C)(C)C#N)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)no1 ZINC000036268795

ZINC000036268795 (search)

C[C@@H](c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)C1CC1)c1ccc(S(C)(=O)=O)cc1 ZINC000036268800

ZINC000036268800 (search)

CC(C)NC(=O)N(Cc1cc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)ccc1Cl)c1ccc(S(C)(=O)=O)cc1 ZINC000036268807

ZINC000036268807 (search)

CC(C)(c1cc(-c2cccc(NC(=O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O ZINC000036268810

ZINC000036268810 (search)

CC(C)(c1cc(-c2cccc(C(=O)Nc3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1)S(C)(=O)=O ZINC000036268814

ZINC000036268814 (search)

CC(C)NC(=O)N(Cc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000036268818

ZINC000036268818 (search)

CC(C)(C#N)c1cc(-c2cccc(CN(C(=O)Nc3ccccc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 ZINC000036268822

ZINC000036268822 (search)

CC(C)OC(=O)N(Cc1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000036268824

ZINC000036268824 (search)

CC(C)(c1cc(-c2cccc(C(N)=O)c2)c2ncccc2c1)S(C)(=O)=O ZINC000036268827

ZINC000036268827 (search)

CC(C)(c1cc(-c2cccc(C(=O)Nc3ccccc3)c2)c2ncccc2c1)S(C)(=O)=O ZINC000036268831

ZINC000036268831 (search)

CC(C)NC(=O)N(Cc1cc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)ccc1F)c1ccc(S(C)(=O)=O)cc1 ZINC000036268834

ZINC000036268834 (search)

CC(C)NC(=O)N(c1ccc(S(C)(=O)=O)cc1)[C@@H](C)c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 ZINC000036268837

ZINC000036268837 (search)

CC(C)(c1cc(-c2cccc(C(=O)Nc3c(Cl)cncc3Cl)c2)c2ncccc2c1)S(C)(=O)=O ZINC000036268843

ZINC000036268843 (search)

CC(C)(C#N)c1cc(-c2cccc(CN(Cc3ccc(F)cc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 ZINC000036268846

ZINC000036268846 (search)

CC(C)(C#N)c1cc(-c2cccc(CN(C(=O)c3ccccc3)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 ZINC000036268850

ZINC000036268850 (search)

CC(C)NC(=O)N(Cc1cccc(-c2cc(C(C)(C)C#N)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 ZINC000036268854

ZINC000036268854 (search)

C[C@@H](c1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)N(C(=O)c1ccc(C(C)(C)O)cc1)c1ccc(S(C)(=O)=O)cc1 ZINC000038377586

ZINC000038377586 (search)

COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(O[C@@H]4CCOC4)c2)CS3)c1 ZINC000043018047

ZINC000043018047 (search)

C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3cnn(C)c3)nn12 ZINC000043176957

ZINC000043176957 (search)

CCOc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 ZINC000058468637

ZINC000058468637 (search)

COc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 ZINC000058575778

ZINC000058575778 (search)

COc1cccc(-c2cc(COc3ccc(C(F)(F)F)cc3)cc3cccnc23)c1 ZINC000058575952

ZINC000058575952 (search)

CS(=O)(=O)c1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 ZINC000058582246

ZINC000058582246 (search)

N#CCCc1ccc(OCc2cc(-c3cccc(F)c3)c3ncccc3c2)cc1 ZINC000058582880

ZINC000058582880 (search)

N#CCCc1ccc(OCc2cc(-c3ccccc3)c3ncccc3c2)cc1 ZINC000058583383

ZINC000058583383 (search)

COC(=O)Cc1ccc(OCc2cc(-c3cccc(OC)c3)c3ncccc3c2)cc1 ZINC000058583436

ZINC000058583436 (search)

COc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 ZINC000058590507

ZINC000058590507 (search)

O=C(O)Cc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 ZINC000058591249

ZINC000058591249 (search)

CC(C)(O)CCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 ZINC000058591391

ZINC000058591391 (search)

COc1cccc(-c2cc(COc3ccccc3Cl)cc3cccnc23)c1 ZINC000058591771

ZINC000058591771 (search)

COc1cccc(-c2cc(COc3cccc(Cl)c3)cc3cccnc23)c1 ZINC000058591773

ZINC000058591773 (search)

Cc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 ZINC000058592839

ZINC000058592839 (search)

N#CCCc1ccc(OCc2cc(-c3cccc(OC(F)F)c3)c3ncccc3c2)cc1 ZINC000058650345

ZINC000058650345 (search)

COc1ccc(/C=N/N(C)C(=O)c2ccc(O)cc2)cc1OC ZINC000095554147

ZINC000095554147 (search)

COc1ccc(C(=O)N(C)/N=C/c2ccc(OC)c(OC)c2)cc1 ZINC000095555937

ZINC000095555937 (search)

COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCCCCOc1ccc(-c2nnn[nH]2)cc1 ZINC000095557067

ZINC000095557067 (search)

C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc(F)c(F)c3)nn12 ZINC000096284612

ZINC000096284612 (search)

C[C@@H](c1ccc2ncccc2c1)c1nnc2ccc(-c3cccc(C#N)c3)nn12 ZINC000096284615

ZINC000096284615 (search)

C[C@@H](c1ccc2ncccc2c1)n1nnc2ncc(-c3cnn(C)c3)nc21 ZINC000096284622

ZINC000096284622 (search)

C[C@@H](c1ccc2ncccc2c1)n1nnc2ncc(-c3cnn(CCO)c3)nc21 ZINC000096284623

ZINC000096284623 (search)

COc1ccc([C@]2(C#N)CC[C@@H](C(=O)O)CC2)cc1OC1CCCC1 ZINC000100042108

ZINC000100042108 (search)

O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OCC2CC2)c1 ZINC001772573152

ZINC001772573152 (search)

O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OC2CCCC2)c1 ZINC001772616388

ZINC001772616388 (search)

O=C(Nc1ccccc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 ZINC001772639812

ZINC001772639812 (search)

O=C(Nc1ccccc1Cl)c1ccc(OC(F)F)c(OC2CCCC2)c1 ZINC001772642412

ZINC001772642412 (search)