Pde5a

Reference Set (77 Compounds)

CN1CC(=O)N2[C@H](c3ccc(Br)s3)c3[nH]c4ccccc4c3C[C@@H]2C1=O ZINC000033965035

ZINC000033965035 (search)

Cc1ccc([C@@H]2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(C)CC(=O)N23)s1 ZINC000142491209

ZINC000142491209 (search)

O=c1c2c([nH]c3ccccc13)[C@@H](c1ccc3c(c1)CCO3)N(c1ncc(-c3ccccn3)cn1)C2 ZINC000003942889

ZINC000003942889 (search)

O=c1c2c([nH]c3ccccc13)[C@@H](c1ccc3c(c1)CCO3)N(c1ccccn1)C2 ZINC000028100198

ZINC000028100198 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ccc(-c3ccccn3)cn1)C2 ZINC000013612975

ZINC000013612975 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ccc(-c3cncn3Cc3ccccc3)cn1)C2 ZINC000028103888

ZINC000028103888 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3occc3c1)N(c1ncc(-c3ccccn3)cn1)C2 ZINC000013612964

ZINC000013612964 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ncc(-c3ccncc3)cn1)C2 ZINC000013612991

ZINC000013612991 (search)

Cc1ncc(-c2cnc(N3Cc4c([nH]c5ccccc5c4=O)[C@@H]3c3ccc4c(c3)CCO4)nc2)n1C ZINC000013612969

ZINC000013612969 (search)

Cc1ncc(-c2cnc(N3Cc4c([nH]c5ccccc5c4=O)[C@@H]3c3ccc4c(c3)CCO4)nc2)n1Cc1ccccc1 ZINC000028103825

ZINC000028103825 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)OCO3)N(c1ncc(-c3cccnc3)cn1)C2 ZINC000013613018

ZINC000013613018 (search)

CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 ZINC000019796168

ZINC000019796168 (search)

Cn1cncc1-c1ccc(N2Cc3c([nH]c4ccccc4c3=O)[C@@H]2c2ccc3c(c2)CCO3)nc1 ZINC000013612998

ZINC000013612998 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ncc(-c3cccnc3)cn1)C2 ZINC000013612985

ZINC000013612985 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ncc(-c3ccccn3)cn1)C2 ZINC000000593367

ZINC000000593367 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ccc(-n3ccnc3)cc1)C2 ZINC000013613007

ZINC000013613007 (search)

COc1ccc(-c2cnc(N3Cc4c([nH]c5ccccc5c4=O)[C@H]3c3ccc4c(c3)CCO4)nc2)cc1 ZINC000003942890

ZINC000003942890 (search)

CCN(CC)CCOc1ccc(-c2cnc(N3Cc4c([nH]c5ccccc5c4=O)[C@@H]3c3ccc4c(c3)CCO4)nc2)cc1 ZINC000027416767

ZINC000027416767 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ccccn1)C2 ZINC000013613004

ZINC000013613004 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)OCO3)N(c1ccc(-n3ccnc3)cc1)C2 ZINC000012360863

ZINC000012360863 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ncc(Br)cn1)C2 ZINC000013612980

ZINC000013612980 (search)

COc1cc(O)c(CC=C(C)C)c2oc(-c3ccc(O)cc3)c(O)c(=O)c12 ZINC000004199939

ZINC000004199939 (search)

O=c1c2c([nH]c3ccccc13)[C@H](c1ccc3c(c1)CCO3)N(c1ccc(-c3ccccn3)nc1)C2 ZINC000013613013

ZINC000013613013 (search)

CCCOc1ccc(NC(=O)c2cccs2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000012360834

ZINC000012360834 (search)

CCCOc1ccc(NC(=O)c2ccc(F)cc2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755579

ZINC000013755579 (search)

CCCOc1ccc(-c2n[nH]c(-c3ccccc3)n2)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755587

ZINC000013755587 (search)

CCCOc1ccc(N)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755574

ZINC000013755574 (search)

CCCOc1ccc(NC(C)=O)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755578

ZINC000013755578 (search)

CCCOc1ccc(NC(C)=O)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000001541550

ZINC000001541550 (search)

CCCOc1ccc(NC(=S)NC(=O)OCC)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755585

ZINC000013755585 (search)

CCCOc1ccc(NC(=O)Nc2ccc(F)cc2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755586

ZINC000013755586 (search)

CCCOc1ccc([N+](=O)[O-])cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755572

ZINC000013755572 (search)

CCCOc1ccc(NC(=O)NCC)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755583

ZINC000013755583 (search)

CCCOc1ccc(NC(=S)NCC)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755584

ZINC000013755584 (search)

CCCOc1ccc(-c2nc(C)cs2)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000001541551

ZINC000001541551 (search)

CCCOc1ccc(-c2csc(C)n2)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000001541552

ZINC000001541552 (search)

CCCOc1ccc(-c2csc(-c3cccnc3)n2)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000001541553

ZINC000001541553 (search)

CCCOc1ccc(-c2n[nH]c(-c3ccccc3)n2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000012360860

ZINC000012360860 (search)

CCCOc1ccccc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755566

ZINC000013755566 (search)

CCCOc1ccc([N+](=O)[O-])cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755571

ZINC000013755571 (search)

CCCOc1ccc(NC(=O)OC)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755581

ZINC000013755581 (search)

CCCOc1ccc(-c2ccc(C)s2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755588

ZINC000013755588 (search)

CCCOc1ccc(-c2nccs2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755589

ZINC000013755589 (search)

CCCOc1ccccc1-c1nc2c(c(C)nn2CCC)c(=O)[nH]1 ZINC000013755567

ZINC000013755567 (search)

CCCOc1ccc(-c2csc(C)n2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000001541554

ZINC000001541554 (search)

CCCOc1ccccc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755560

ZINC000013755560 (search)

CCCOc1ccccc1-c1nc2c(c(C)nn2C(C)(C)C)c(=O)[nH]1 ZINC000013755569

ZINC000013755569 (search)

CCCOc1ccc(NS(C)(=O)=O)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755577

ZINC000013755577 (search)

CCCOc1ccc(-c2csc(-c3ccccc3)n2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755591

ZINC000013755591 (search)

CCCOc1ccc(-c2csc(-c3ccccc3)n2)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755592

ZINC000013755592 (search)

CCCOc1ccc(-c2cccs2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000012360790

ZINC000012360790 (search)

CCCOc1ccc(C(=O)CN2CCOCC2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000012360841

ZINC000012360841 (search)

CCCOc1ccc(N)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755573

ZINC000013755573 (search)

CCCOc1ccc(N(C)C)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755575

ZINC000013755575 (search)

CCCOc1ccc(NS(C)(=O)=O)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000001541556

ZINC000001541556 (search)

CCCOc1ccccc1-c1nc2c(c(C)nn2Cc2ccccc2)c(=O)[nH]1 ZINC000012360806

ZINC000012360806 (search)

CCCOc1ccc(NC(=O)CN2CCN(C)CC2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000022938344

ZINC000022938344 (search)

CCCOc1ccc(-c2nc(C)cs2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755590

ZINC000013755590 (search)

C=C(C)[C@H](CC=C(C)C)Cc1c(O)cc(OC)c(C(=O)/C=C/c2ccc(O)cc2O)c1O ZINC000013817033

ZINC000013817033 (search)

CCCOc1ccccc1-c1nc2scc(C)c2c(=O)[nH]1 ZINC000013755557

ZINC000013755557 (search)

CCCOc1ccc(NC(N)=O)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000002001930

ZINC000002001930 (search)

CCCCn1nc(C)c2c(=O)[nH]c(-c3ccccc3OCCC)nc21 ZINC000013755568

ZINC000013755568 (search)

CCCOc1ccccc1-c1nc2ccsc2c(=O)[nH]1 ZINC000013755558

ZINC000013755558 (search)

Cc1nn(C)c2nc(-c3ccccc3OC(C)C)[nH]c(=O)c12 ZINC000013755564

ZINC000013755564 (search)

CCCOc1ccc(NC(N)=S)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755582

ZINC000013755582 (search)

CCCOc1ccccc1-c1nc2c(C)csc2c(=O)[nH]1 ZINC000013755559

ZINC000013755559 (search)

CCCOc1ccccc1-c1nc2nsc(C)c2c(=O)[nH]1 ZINC000013755562

ZINC000013755562 (search)

CCCOc1ccccc1-c1nc2c(c(C)nn2CC(F)(F)F)c(=O)[nH]1 ZINC000013755570

ZINC000013755570 (search)

CCCOc1ccc(N(C)C)cc1-c1nc2c(c(C)nn2CC)c(=O)[nH]1 ZINC000013755576

ZINC000013755576 (search)

CCCOc1ccccc1-c1nc2cnccc2c(=O)[nH]1 ZINC000003800960

ZINC000003800960 (search)

CCCOc1ccccc1-c1nc2[nH]cnc2c(=O)[nH]1 ZINC000013755555

ZINC000013755555 (search)

CCOc1ccccc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 ZINC000013755563

ZINC000013755563 (search)

CCCOc1ccccc1-c1nc2sccc2c(=O)[nH]1 ZINC000001914216

ZINC000001914216 (search)

C=C(C)[C@H](CCC(C)(C)O)Cc1c(O)cc(OC)c2c1O[C@H](c1ccc(O)cc1O)[C@@H](O)C2=O ZINC000013817006

ZINC000013817006 (search)

C=C(C)[C@H](CCC(C)(C)O)Cc1c(O)cc(OC)c2c1O[C@H](c1ccc(O)cc1O)CC2=O ZINC000013817026

ZINC000013817026 (search)

CCCOc1ccccc1-c1nc2ncncc2c(=O)[nH]1 ZINC000013755556

ZINC000013755556 (search)

CCCOc1ccccc1-c1nc2ccncc2c(=O)[nH]1 ZINC000003800961

ZINC000003800961 (search)