PDE6D

Reference Set (87 Compounds)

O=C(OC[C@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000098207928

ZINC000098207928 (search)

Cc1ccc(-n2nc3c(=O)n(CCC(=O)N4CCC(N5C(=O)c6ccccc6N[C@@H]5c5ccccc5F)CC4)nc(C)c3c2C)cc1 ZINC001772601203

ZINC001772601203 (search)

c1ccc(Cn2c(-c3ccc(OC[C@H](C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 ZINC000102240258

ZINC000102240258 (search)

Cc1ccc(-n2nc3c(=O)n(CCCC(=O)NC[C@H](C)c4ccccc4)nc(C)c3c2C)cc1 ZINC000015942953

ZINC000015942953 (search)

O=C1c2ccccc2N[C@@H](c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3N[C@H]2c2ccccc2F)CC1 ZINC001772622824

ZINC001772622824 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCCCCCN1C(=O)c2ccccc2N[C@@H]1c1ccccc1F ZINC001772637307

ZINC001772637307 (search)

Cc1ccc(-n2nc3c(=O)n(CCCN4CCC(N5C(=O)c6ccccc6N[C@@H]5c5ccccc5F)CC4)nc(C)c3c2C)cc1 ZINC001772658050

ZINC001772658050 (search)

O=C1c2cc(F)ccc2N[C@H](c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 ZINC001772598531

ZINC001772598531 (search)

Cc1nc2ccccc2n1CCOC(=O)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000169353298

ZINC000169353298 (search)

O=C(OC[C@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 ZINC000169353026

ZINC000169353026 (search)

O=C(OCCn1ccnc1-c1ccccc1)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000169353297

ZINC000169353297 (search)

c1ccc(Cn2c(-c3ccc(OCCn4ccnc4-c4ccccc4)cc3)nc3ccccc32)cc1 ZINC000169353300

ZINC000169353300 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCCCCN1C(=O)c2ccccc2N[C@@H]1c1ccccc1F ZINC001772615794

ZINC001772615794 (search)

CC(C)c1nc2ccccc2n1[C@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 ZINC000169353293

ZINC000169353293 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 ZINC001772581954

ZINC001772581954 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCCCCCCN1C(=O)c2ccccc2N[C@H]1c1ccccc1F ZINC001772612136

ZINC001772612136 (search)

O=C(OC[C@@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 ZINC000169353025

ZINC000169353025 (search)

CCc1nc2ccccc2n1[C@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 ZINC000169353295

ZINC000169353295 (search)

Cc1ccc2c(c1)C(=O)N(CCOc1ccc(-c3nc4ccccc4n3Cc3ccncc3)cc1)[C@@H](c1ccccc1F)N2 ZINC001772585916

ZINC001772585916 (search)

COc1ccc2c(c1)N[C@H](c1ccccc1F)N(CCOc1ccc(-c3nc4ccccc4n3Cc3ccncc3)cc1)C2=O ZINC001772656532

ZINC001772656532 (search)

O=C(OC[C@@H]([C@@H]1CCCNC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000169353029

ZINC000169353029 (search)

O=C1c2cc(Cl)ccc2N[C@H](c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 ZINC001772607711

ZINC001772607711 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1C1CCN(CCN2C(=O)c3ccccc3N[C@H]2c2ccccc2F)CC1 ZINC001772574060

ZINC001772574060 (search)

O=C(OC[C@H](C1CCNCC1)n1c(C2CC2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 ZINC000169353294

ZINC000169353294 (search)

O=C1c2ccc(F)cc2N[C@H](c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 ZINC001772579453

ZINC001772579453 (search)

O=C(OC[C@@H]([C@@H]1CCNC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000169353285

ZINC000169353285 (search)

O=C(OC[C@@H](CC1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000169353289

ZINC000169353289 (search)

O=C(OCCn1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000169353299

ZINC000169353299 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CC1CCC(CN2C(=O)c3ccccc3N[C@@H]2c2ccccc2F)CC1 ZINC001772604942

ZINC001772604942 (search)

O=C1c2ccc(Cl)cc2N[C@H](c2ccccc2F)N1CCOc1ccc(-c2nc3ccccc3n2Cc2ccncc2)cc1 ZINC001772645087

ZINC001772645087 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCOc1ccc(N2C(=O)c3ccccc3N[C@@H]2c2ccccc2F)cc1 ZINC001772640651

ZINC001772640651 (search)

c1ccc(Cn2c(-c3ccc(OC[C@@H](C4CCCCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 ZINC000146278927

ZINC000146278927 (search)

O=C(OC[C@@H](C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 ZINC000169353027

ZINC000169353027 (search)

CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)N1CCOCC1 ZINC000169353307

ZINC000169353307 (search)

CC(C)[C@@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1)n1c(-c2ccccc2)nc2ccccc21 ZINC000169353015

ZINC000169353015 (search)

Cc1nc2ccccc2n1CCOc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1 ZINC000169353301

ZINC000169353301 (search)

CC(C)[C@@H](COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 ZINC000169352999

ZINC000169352999 (search)

O=C1c2ccccc2N[C@@H](c2ccccn2)N1c1ccc(OCCn2ccnc2-c2ccccc2)cc1 ZINC001772654058

ZINC001772654058 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCN1CCC(CN2C(=O)c3ccccc3N[C@@H]2c2ccccc2F)CC1 ZINC001772621979

ZINC001772621979 (search)

O=C(OC[C@@H](C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000146381838

ZINC000146381838 (search)

CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 ZINC000169353309

ZINC000169353309 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1c1ccc(OCCn2ccnc2-c2ccccc2)cc1 ZINC001772644358

ZINC001772644358 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3N[C@H]2c2ccccc2F)CC1 ZINC001772622825

ZINC001772622825 (search)

O=C(OC[C@@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)N1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 ZINC000146349860

ZINC000146349860 (search)

Cc1nc2ccccc2n1[C@H](COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 ZINC000169353296

ZINC000169353296 (search)

CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(=O)NCCN(C)C ZINC000169353305

ZINC000169353305 (search)

COCCOCCOCCCNC(=O)C[C@H](O)C[C@H](O)CCn1c(-c2ccc(F)cc2)c(-c2ccccc2)c(C(=O)Nc2ccccc2)c1C(C)C ZINC000169353308

ZINC000169353308 (search)

CN1c2ccc(F)cc2C(=O)N(C2CCN(CCCn3ccnc3-c3ccccc3)CC2)[C@H]1c1ccccc1F ZINC001772634659

ZINC001772634659 (search)

O=C1c2cc(F)ccc2N(CC2CC2)[C@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772617107

ZINC001772617107 (search)

C=CC[C@H](COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 ZINC000098207989

ZINC000098207989 (search)

O=C1c2cc(F)ccc2N(CC2CCC2)[C@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772580423

ZINC001772580423 (search)

Cc1nccn1CCOc1ccc(N2C(=O)c3ccccc3N[C@H]2c2ccccc2F)cc1 ZINC001772626875

ZINC001772626875 (search)

Cc1ccc2c(c1)C(=O)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)[C@@H](c1ccccc1F)N2 ZINC001772646002

ZINC001772646002 (search)

O=C1c2cc(F)ccc2N(CC2CCCC2)[C@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772579447

ZINC001772579447 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772642568

ZINC001772642568 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCCCN1C(=O)c2ccccc2N[C@@H]1c1ccccc1F ZINC001772578470

ZINC001772578470 (search)

O=C(OC[C@@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2c(F)cccc2Cl)CC1 ZINC000169353018

ZINC000169353018 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1c1ccc(OCCn2ccnc2)cc1 ZINC001772623927

ZINC001772623927 (search)

O=C1c2cc(F)ccc2N(CC2CCCCC2)[C@@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772622343

ZINC001772622343 (search)

C=CC(=O)Oc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1 ZINC000169353302

ZINC000169353302 (search)

O=C1c2cc(F)ccc2N[C@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772583628

ZINC001772583628 (search)

O=C1c2ccc(F)cc2N[C@H](c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 ZINC001772650393

ZINC001772650393 (search)

Cc1ccc2c(c1)N[C@H](c1ccccc1F)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)C2=O ZINC001772657330

ZINC001772657330 (search)

C=CC(=O)N1CCC([C@@H](COc2ccc(-c3nc4ccccc4n3Cc3ccccc3)cc2)n2c(-c3ccccc3)nc3ccccc32)CC1 ZINC000169353304

ZINC000169353304 (search)

O=C(OC[C@@H](C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2c(F)cccc2Cl)CC1 ZINC000169353021

ZINC000169353021 (search)

Cc1nc2ccccc2n1CCOc1ccc(N2C(=O)c3ccccc3N[C@H]2c2ccccc2F)cc1 ZINC001772626880

ZINC001772626880 (search)

COc1ccc2c(c1)C(=O)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)[C@@H](c1ccccc1F)N2 ZINC001772640594

ZINC001772640594 (search)

c1ccc(Cn2c(-c3ccc(OC[C@@H](CC4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 ZINC000169353009

ZINC000169353009 (search)

c1ccc(Cn2c(-c3ccccc3)nc3ccccc32)cc1 ZINC000000997179

ZINC000000997179 (search)

Cc1nccn1CCOc1ccc(N2C(=O)c3ccccc3N[C@@H]2c2ccccn2)cc1 ZINC001772642756

ZINC001772642756 (search)

COc1ccc2c(c1)N[C@H](c1ccccc1F)N(C1CCN(CCCn3ccnc3-c3ccccc3)CC1)C2=O ZINC001772623753

ZINC001772623753 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1c1ccc(OCCn2c(-c3ccccc3)nc3ccccc32)cc1 ZINC001772609472

ZINC001772609472 (search)

O=C1c2ccccc2N[C@@H](c2ccccn2)N1c1ccc(OCCn2ccnc2)cc1 ZINC001772607387

ZINC001772607387 (search)

Cc1cccc(Cn2c(-c3ccc(OC[C@@H](C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)c1 ZINC000146435125

ZINC000146435125 (search)

O=C1c2ccccc2N[C@@H](c2ccccn2)N1c1ccc(OCCn2c(-c3ccccc3)nc3ccccc32)cc1 ZINC001772587409

ZINC001772587409 (search)

c1ccc(Cn2c(-c3ccc(OC[C@@H]([C@@H]4CCCNC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 ZINC000169353005

ZINC000169353005 (search)

O=C1c2cccc3cccc(c23)N1c1ccc(-c2ccccc2)cc1 ZINC000001229590

ZINC000001229590 (search)

c1ccc(-c2nc3ccccc3n2[C@@H](COc2ccc(-c3nc4ccccc4n3Cc3cccnc3)cc2)C2CCNCC2)cc1 ZINC000169353011

ZINC000169353011 (search)

Fc1ccc(Cn2c(-c3ccc(OC[C@@H](C4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 ZINC000146285518

ZINC000146285518 (search)

Cc1nccn1CCCn1c(-c2ccccc2)cc(-c2nc3ccccc3n2CC2CC2)c1C(C)C ZINC000169353311

ZINC000169353311 (search)

Cc1nccn1CCCn1c(-c2ccccc2)cc(-c2nc3ccccc3n2CC2CCCC2)c1C(C)C ZINC000169353312

ZINC000169353312 (search)

Cc1ccccc1Cn1c(-c2ccc(OC[C@@H](C3CCNCC3)n3c(-c4ccccc4)nc4ccccc43)cc2)nc2ccccc21 ZINC000146268623

ZINC000146268623 (search)

Cc1nccn1CCCn1c(-c2ccccc2)cc(-c2nc3ccccc3n2Cc2ccccc2)c1C(C)C ZINC000169353313

ZINC000169353313 (search)

O=C(NC[C@@H](C1CCNCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1 ZINC000169353291

ZINC000169353291 (search)

O=C(O)C[C@@H](COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 ZINC000146289514

ZINC000146289514 (search)

O=C1c2ccccc2N[C@H](c2ccccc2F)N1CCN1CCC(N2C(=O)c3ccccc3N[C@@H]2c2ccccc2F)CC1 ZINC001772581309

ZINC001772581309 (search)

CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)O ZINC000001535101

ZINC000001535101 (search)