PDE8B

Reference Set (129 Compounds)

Cc1oc(-c2ccccc2)nc1CN1C[C@H](c2ccccc2)C[C@@H](C(=O)NCc2cccc(N)n2)C1 ZINC000071340499

ZINC000071340499 (search)

Cc1cccc(CNC(=O)[C@@H]2C[C@@H](c3ccccc3)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071332053

ZINC000071332053 (search)

CC[C@H]1C[C@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071333977

ZINC000071333977 (search)

COC[C@@H]1C[C@@H](C(=O)NCC2CCOCC2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071331875

ZINC000071331875 (search)

CC[C@@H]1C[C@@H](C(=O)NC[C@H]2CCCO2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071340666

ZINC000071340666 (search)

COC[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071331850

ZINC000071331850 (search)

Cc1cccc(CNC(=O)[C@H]2C[C@H](c3nc(C)no3)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071333167

ZINC000071333167 (search)

Cc1cccc(CNC(=O)[C@@H]2C[C@@H](c3nc(C)no3)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071335398

ZINC000071335398 (search)

COC[C@H]1C[C@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071341060

ZINC000071341060 (search)

COC[C@@H]1C[C@@H](C(=O)NC[C@H]2CCCO2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071340613

ZINC000071340613 (search)

CC[C@@H]1C[C@@H](C(=O)NCc2cccc(N)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071332440

ZINC000071332440 (search)

Cc1cccc(CNC(=O)[C@@H]2CN(Cc3nc(-c4ccccc4)oc3C)Cc3ccccc32)n1 ZINC000071331175

ZINC000071331175 (search)

CC[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071334039

ZINC000071334039 (search)

CCC[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071334187

ZINC000071334187 (search)

CC(=O)O[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071332606

ZINC000071332606 (search)

CC[C@@H]1C[C@@H](C(=O)NCC2CCOCC2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071333542

ZINC000071333542 (search)

COC[C@@H]1C[C@@H](C(=O)NCC2CCOCC2)CN(Cc2[nH]c(-c3ccncn3)nc2C)C1 ZINC000071334621

ZINC000071334621 (search)

CCCC[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071331138

ZINC000071331138 (search)

CC[C@@H]1C[C@@H](C(=O)NCc2cccc(N)n2)CN(Cc2nc(N3CCOCC3)oc2C)C1 ZINC000071411293

ZINC000071411293 (search)

CC[C@@H]1C[C@@H](C(=O)NC[C@@H]2CCCO2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071332694

ZINC000071332694 (search)

CC[C@@H]1C[C@@H](C(=O)NC[C@H]2CCCO2)CN(Cc2nc(-c3ccncn3)[nH]c2C)C1 ZINC000071331566

ZINC000071331566 (search)

CC[C@@H]1C[C@@H](C(=O)NC[C@@H]2CCCO2)CN(Cc2nc(-c3ccncn3)[nH]c2C)C1 ZINC000071340838

ZINC000071340838 (search)

Cc1noc([C@@H]2C[C@@H](C(=O)NC[C@@H]3CCCO3)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071341214

ZINC000071341214 (search)

Cc1cccc(CNC(=O)[C@@H]2C[C@@H](C)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071340641

ZINC000071340641 (search)

COC[C@H]1C[C@@H](C(=O)NC[C@H]2CCCO2)CN(Cc2nc(N3CCOCC3)oc2C)C1 ZINC000071333393

ZINC000071333393 (search)

COC[C@@H]1C[C@@H](C(=O)NCC2CCOCC2)CN(Cc2nc(N3CCOCC3)oc2C)C1 ZINC000071335123

ZINC000071335123 (search)

Cc1oc(-c2ccccc2)nc1CN1CCC[C@@H](C(=O)NCc2cccc(N)n2)C1 ZINC000071335158

ZINC000071335158 (search)

COC[C@@H]1C[C@@H](C(=O)NC[C@H]2CCCO2)CN(Cc2nc(N3CCOCC3)oc2C)C1 ZINC000071335445

ZINC000071335445 (search)

Cc1cccc(CNC(=O)[C@H]2C[C@H](c3nnc(C)o3)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071410850

ZINC000071410850 (search)

Cc1cccc(CNC(=O)[C@@H]2C[C@@H](c3nnc(C)o3)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071332856

ZINC000071332856 (search)

CCNC(=O)O[C@@H]1C[C@@H](C(=O)NCc2cccc(C)n2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071340341

ZINC000071340341 (search)

Cc1oc(-c2ccccc2)nc1CN1CCC[C@@H](C(=O)NC[C@H]2CCCO2)C1 ZINC000071341433

ZINC000071341433 (search)

CC[C@@H]1C[C@@H](C(=O)NCC2CCOCC2)CN(Cc2nc(N3CCOCC3)oc2C)C1 ZINC000071341395

ZINC000071341395 (search)

Cc1cccc(CNC(=O)[C@@H]2CCCN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071340304

ZINC000071340304 (search)

Cc1oc(-c2ccccc2)nc1CN1CCC[C@@H](C(=O)NC[C@@H]2CCCO2)C1 ZINC000071340871

ZINC000071340871 (search)

Cc1cccc(CNC(=O)[C@]2(F)CN(Cc3nc(-c4ccccc4)oc3C)Cc3ccccc32)n1 ZINC000071331861

ZINC000071331861 (search)

Cc1oc(-c2ccccc2)nc1CN1CCC[C@H](C(=O)NCC2CCOCC2)C1 ZINC000071334324

ZINC000071334324 (search)

CC[C@H]1C[C@@H](C(=O)NC[C@H]2CCCO2)CN(Cc2nc(-c3ccccc3)oc2C)C1 ZINC000071340816

ZINC000071340816 (search)

CC[C@@H]1C[C@@H](C(=O)NC[C@@H]2CCCO2)CN(Cc2nc(N3CCOCC3)oc2C)C1 ZINC000071332642

ZINC000071332642 (search)

Cc1cccc(CNC(=O)[C@H]2CN(Cc3nc(-c4ccccc4)oc3C)C[C@@H]2C(F)(F)F)n1 ZINC000071331810

ZINC000071331810 (search)

Cc1cccc(CNC(=O)[C@@H]2CN(Cc3nc(-c4ccccc4)oc3C)CCS2(=O)=O)n1 ZINC000071334597

ZINC000071334597 (search)

Cc1cccc(CNC(=O)[C@@H]2C[C@@H](O)CN(Cc3nc(-c4ccccc4)oc3C)C2)n1 ZINC000071340579

ZINC000071340579 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@H]1CN(Cc2nccs2)CCO1 ZINC000084687879

ZINC000084687879 (search)

Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1 ZINC000084690183

ZINC000084690183 (search)

Nc1nc(C(F)(F)F)nc2c1nnn2C[C@H]1CN(Cc2ccccn2)CCO1 ZINC000084690757

ZINC000084690757 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@H]1OCCc2ccccc21 ZINC000084668145

ZINC000084668145 (search)

CCc1csc(CN2CCO[C@@H](Cn3nnc4c(N)nc(C)nc43)C2)n1 ZINC000084690471

ZINC000084690471 (search)

CC(C)(C)c1cc(Cn2nnc3c(N)nc(C4CC4)nc32)n[nH]1 ZINC000084712129

ZINC000084712129 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1cc(C2CC2)n[nH]1 ZINC000084688785

ZINC000084688785 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084708752

ZINC000084708752 (search)

Nc1nc(CSc2ccccc2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084688762

ZINC000084688762 (search)

Cc1nc(-c2nc(N)c3nnn(C[C@@H]4CCCCO4)c3n2)cs1 ZINC000084688465

ZINC000084688465 (search)

Nc1nc(C(F)(F)F)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084689802

ZINC000084689802 (search)

Nc1nc(C(F)(F)F)nc2c1nnn2C[C@H]1CCCO1 ZINC000084689804

ZINC000084689804 (search)

COc1ccc2c(N[C@@H](C)Cc3cc(C)n[nH]3)ncnc2c1OC ZINC000098207841

ZINC000098207841 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1ccc2c(c1)CCO2 ZINC000084690234

ZINC000084690234 (search)

Nc1nc(COc2cccc(F)c2)nc2c1nnn2C[C@@H]1CCCO1 ZINC000084690684

ZINC000084690684 (search)

Nc1nc(-c2cccs2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084705011

ZINC000084705011 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1ccc2c(c1)OCCO2 ZINC000084690419

ZINC000084690419 (search)

Cc1nc(N)c2nnn(C[C@H]3CN(Cc4cc(F)cc(F)c4)CCO3)c2n1 ZINC000084690472

ZINC000084690472 (search)

CC(C)(C)OC(=O)N1CCCC[C@@H]1Cn1nnc2c(N)nc(C3CC3)nc21 ZINC000084712123

ZINC000084712123 (search)

CCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084729748

ZINC000084729748 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@H]1CN(Cc2ncccn2)CCO1 ZINC000084690182

ZINC000084690182 (search)

Cc1ccnc(N2CCC[C@H](Cn3nnc4c(N)nc(C5CC5)nc43)C2)n1 ZINC000084690847

ZINC000084690847 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@H]1CCCO1 ZINC000084708771

ZINC000084708771 (search)

Cc1ccn2cc(Cn3nnc4c(N)nc(C5CC5)nc43)nc2c1 ZINC000084544563

ZINC000084544563 (search)

CN1Cc2ccccc2C[C@@H]1Cn1nnc2c(N)nc(C3CC3)nc21 ZINC000084704004

ZINC000084704004 (search)

C[C@@H](c1ccc2[nH]ccc2c1)n1nnc2c(N)nc(C3CC3)nc21 ZINC000084690235

ZINC000084690235 (search)

Cc1cn2cc(Cn3nnc4c(N)nc(C5CC5)nc43)nc2s1 ZINC000084729578

ZINC000084729578 (search)

CCCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084729680

ZINC000084729680 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@@H]1CN(Cc2ccccc2)CCO1 ZINC000084690755

ZINC000084690755 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1nc2ccccc2c(=O)[nH]1 ZINC000084690237

ZINC000084690237 (search)

Cc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084688734

ZINC000084688734 (search)

Cc1cccc(C[C@@H](C)n2nnc3c(N)nc(C4CC4)nc32)n1 ZINC000084704008

ZINC000084704008 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1cnn(-c2ccccc2)n1 ZINC000084687195

ZINC000084687195 (search)

Cc1cccn2cc(Cn3nnc4c(N)nc(C5CC5)nc43)nc12 ZINC000084712127

ZINC000084712127 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1nc(-c2ccccc2)n[nH]1 ZINC000084688056

ZINC000084688056 (search)

Nc1nc(Cc2ccccc2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084688758

ZINC000084688758 (search)

COC(=O)Cc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084705016

ZINC000084705016 (search)

CC(C)CCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084707379

ZINC000084707379 (search)

C[C@@H](C1CCCCC1)n1nnc2c(N)nc(C3CC3)nc21 ZINC000084904594

ZINC000084904594 (search)

Nc1nc(CC(=O)O)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084688463

ZINC000084688463 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1ccc(C(F)(F)F)cc1 ZINC000084690964

ZINC000084690964 (search)

Cc1ncsc1CCn1nnc2c(N)nc(C3CC3)nc21 ZINC000084910613

ZINC000084910613 (search)

CC(C)S(=O)(=O)Cc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084708759

ZINC000084708759 (search)

Nc1nc(-c2ccco2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084729736

ZINC000084729736 (search)

Nc1nc(C2CC2)nc2c1nnn2Cc1ccc(Cl)cc1 ZINC000084709606

ZINC000084709606 (search)

Nc1nc(Cc2cccs2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084672258

ZINC000084672258 (search)

CC(C)c1nc(N[C@@H](CN2CCCCC2)c2ccccc2)c2nnn(Cc3ccccc3)c2n1 ZINC000084689278

ZINC000084689278 (search)

COc1ccc(Cn2nnc3c(N)nc(C#N)nc32)cc1 ZINC000084729674

ZINC000084729674 (search)

COCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084708755

ZINC000084708755 (search)

CCc1cnc(N2CC[C@@H](Cn3nnc4c(N)nc(C5CC5)nc43)C2)nc1 ZINC000084688788

ZINC000084688788 (search)

CCc1nc(Cn2nnc3c(N)nc(C4CC4)nc32)cs1 ZINC000084688787

ZINC000084688787 (search)

CC(=O)OCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084688177

ZINC000084688177 (search)

CC(C)n1cc(Cn2nnc3c(N)nc(C4CC4)nc32)cn1 ZINC000084688786

ZINC000084688786 (search)

Nc1nc(C2CC2)nc2c1nnn2CCSCc1ccco1 ZINC000084690238

ZINC000084690238 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@H]1CCCOC1 ZINC000084687881

ZINC000084687881 (search)

Nc1nc(-c2ccccc2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084708763

ZINC000084708763 (search)

CSCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084688175

ZINC000084688175 (search)

N#CCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084707508

ZINC000084707508 (search)

CC(C)Cc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084688760

ZINC000084688760 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@@H]1CCN(Cc2nccs2)C1 ZINC000084688789

ZINC000084688789 (search)

Nc1nc(C2CC2)nc2c1nnn2CC1(c2ccccc2)CCOCC1 ZINC000084690967

ZINC000084690967 (search)

CCCCc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084709549

ZINC000084709549 (search)

Nc1nc(C2CCCCC2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084708767

ZINC000084708767 (search)

Nc1nc(C2CCC2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084690597

ZINC000084690597 (search)

Nc1nc([C@@H]2CCCO2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084707522

ZINC000084707522 (search)

COc1ccc(Cn2nnc3c(N)nc(C(N)=O)nc32)cc1 ZINC000084729677

ZINC000084729677 (search)

Nc1nc(Cc2ccsc2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084712225

ZINC000084712225 (search)

COCc1nc(N)c2nnn(C[C@H]3CCCO3)c2n1 ZINC000084690938

ZINC000084690938 (search)

Nc1nc(CC2CC2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084708721

ZINC000084708721 (search)

Nc1nc(-c2cccnc2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084729743

ZINC000084729743 (search)

Cc1cc(-c2nc(N)c3nnn(C[C@@H]4CCCCO4)c3n2)no1 ZINC000084707500

ZINC000084707500 (search)

CCCCN1C[C@H](Cn2nnc3c(N)nc(C4CC4)nc32)OCC1=O ZINC000084690965

ZINC000084690965 (search)

Cc1ccn2cc(Cn3nnc4c(N)nc(C5CC5)nc43)nc2n1 ZINC000084690963

ZINC000084690963 (search)

Nc1nc(Cn2ccnc2)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084688461

ZINC000084688461 (search)

Cn1cc(CCn2nnc3c(N)nc(C4CC4)nc32)cn1 ZINC000084690939

ZINC000084690939 (search)

CN(C)CCNc1nc(C(F)(F)F)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084689800

ZINC000084689800 (search)

Nc1nc(CO)nc2c1nnn2C[C@@H]1CCCCO1 ZINC000084688179

ZINC000084688179 (search)

Nc1nc(C2CC2)nc2c1nnn2CC1CCOCC1 ZINC000084709604

ZINC000084709604 (search)

NC(=O)Cc1nc(N)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084707514

ZINC000084707514 (search)

Nc1ncnc2c1nnn2C[C@@H]1CCCCO1 ZINC000084910619

ZINC000084910619 (search)

FC(F)(F)c1nc(NCc2ccncc2)c2nnn(C[C@H]3CCCO3)c2n1 ZINC000084691028

ZINC000084691028 (search)

COc1ccc2c([C@H]3CCc4ccc(Cl)cc43)nccc2c1OC ZINC000474609628

ZINC000474609628 (search)

Nc1nc(C2CC2)nc2c1nnn2C[C@H]1CCCN(Cc2ccccc2)C1 ZINC000084690849

ZINC000084690849 (search)

COc1ccc(C2=NN(C3CCCCCC3)C(=O)[C@@H]3CC=CC[C@H]23)cc1OCCCCOc1ccc(-c2nnn[nH]2)cc1 ZINC000026569007

ZINC000026569007 (search)

FC(F)(F)c1nc(NC[C@@H]2CCCO2)c2nnn(C[C@@H]3CCCCO3)c2n1 ZINC000084709722

ZINC000084709722 (search)

Cc1ccc(CNc2nc(C(F)(F)F)nc3c2nnn3C[C@H]2CCCO2)o1 ZINC000084690276

ZINC000084690276 (search)

FC(F)(F)c1nc(NCCc2ccco2)c2nnn(C[C@H]3CCCO3)c2n1 ZINC000084690275

ZINC000084690275 (search)