Pik3ca

Reference Set (120 Compounds)

CCn1nc(C2CCN(C(=O)[C@@H](O)CO)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145618138

ZINC000145618138 (search)

CCn1nc(C2CCN(C(=O)CCO)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145460849

ZINC000145460849 (search)

CCn1nc(C2CCN(C(=O)[C@H](O)CO)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145606439

ZINC000145606439 (search)

C[C@H](O)CC(=O)N1CCC(c2nc(-c3cnc(N)c(-c4nnc(C(C)(C)C)o4)n3)n(C)n2)CC1 ZINC000145700280

ZINC000145700280 (search)

CCn1nc(C2CCN(C(=O)CC(=O)O)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145608112

ZINC000145608112 (search)

Cn1nc(C2CCN(C(=O)CCO)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145611032

ZINC000145611032 (search)

Cn1nc(C2CCN(C(=O)C(C)(C)O)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145505181

ZINC000145505181 (search)

C[C@H](CO)C(=O)N1CCC(c2nc(-c3cnc(N)c(-c4nnc(C(C)(C)C)o4)n3)n(C)n2)CC1 ZINC000145535372

ZINC000145535372 (search)

Cn1nc(C2CCN(C(=O)CC(=O)O)CC2)nc1-c1cnc(N)c(-c2nnc(C(C)(C)C)o2)n1 ZINC000145739961

ZINC000145739961 (search)

CC(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5cnc6[nH]ncc6c5)nc4c32)CC1 ZINC000095590439

ZINC000095590439 (search)

COc1cc(N)cc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073156466

ZINC000073156466 (search)

Cc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(=O)[C@H](C)O)CC2)c(=O)n4C)cn1 ZINC000068245474

ZINC000068245474 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCC(N)=O)CC3)c2=O)cc1F ZINC000101675252

ZINC000101675252 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCC(=O)O)CC3)c2=O)cn1 ZINC000261099285

ZINC000261099285 (search)

C[C@H](O)C(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5cccc6[nH]ncc56)nc4c32)CC1 ZINC000095586073

ZINC000095586073 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C1CCCC1 ZINC000084687562

ZINC000084687562 (search)

COc1ccc(-c2ccc3ncc4c(c3n2)n([C@H]2CC[C@H](OCCO)CC2)c(=O)n4C)cn1 ZINC000261097650

ZINC000261097650 (search)

COc1ccc(-c2ccc3ncc4c(c3n2)n([C@H]2CC[C@H](O)CC2)c(=O)n4C)cn1 ZINC000261165425

ZINC000261165425 (search)

Cc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(=O)CO)CC2)c(=O)n4C)cn1 ZINC000095588946

ZINC000095588946 (search)

COc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(C)=O)CC2)c(=O)n4C)cn1 ZINC000095592788

ZINC000095592788 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCCO)CC3)c2=O)cn1 ZINC000117704832

ZINC000117704832 (search)

CC(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5cccc6[nH]ncc56)nc4c32)CC1 ZINC000095587231

ZINC000095587231 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCO)CC3)c2=O)cc1F ZINC000101675194

ZINC000101675194 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCC(N)=O)CC3)c2=O)cc1F ZINC000101675227

ZINC000101675227 (search)

Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073139331

ZINC000073139331 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](O)CC3)c2=O)cn1 ZINC000116025979

ZINC000116025979 (search)

COCC(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5ccc(C)nc5)nc4c32)CC1 ZINC000095588217

ZINC000095588217 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCO)CC3)c2=O)cn1 ZINC000101675192

ZINC000101675192 (search)

CNc1nc(C)c2cc(-c3ccc(OC)nc3)c(=O)n(C3CCCC3)c2n1 ZINC000117703796

ZINC000117703796 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCO)CC3)c2=O)cc1F ZINC000101675279

ZINC000101675279 (search)

Cc1nc(N)nc2c1cc(-c1cccc(CO)c1)c(=O)n2C1CCCC1 ZINC000117767555

ZINC000117767555 (search)

CNc1nc(C)c2cc(-c3cccc(CO)c3)c(=O)n(C3CCCC3)c2n1 ZINC000058650484

ZINC000058650484 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CCCC3)c2=O)cn1 ZINC000084687561

ZINC000084687561 (search)

COc1ccc(-c2ccc3ncc4c(c3n2)n(-c2ccc(C(C)(C)C#N)cc2)c(=O)n4C)cn1 ZINC000095589533

ZINC000095589533 (search)

Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)cc(N2CCOCC2)n1 ZINC000073160253

ZINC000073160253 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCC(N)=O)CC3)c2=O)cn1 ZINC000101675231

ZINC000101675231 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCC(N)=O)CC3)c2=O)cn1 ZINC000101675222

ZINC000101675222 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCC(N)=O)CC3)c2=O)cn1 ZINC000101675246

ZINC000101675246 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCC(N)=O)CC3)c2=O)cn1 ZINC000101675256

ZINC000101675256 (search)

CC(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5ccc(C)nc5)nc4c32)CC1 ZINC000095592029

ZINC000095592029 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n(N3CCCC3)c2=O)cc1F ZINC000084671891

ZINC000084671891 (search)

CNc1cc(OC)c2nc(C(F)F)n(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)c2c1 ZINC000073140698

ZINC000073140698 (search)

COc1ncc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](OCO)CC3)c2=O)cn1 ZINC000101675276

ZINC000101675276 (search)

COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073129640

ZINC000073129640 (search)

CCOc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073129642

ZINC000073129642 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@H](O)CC3)c2=O)cn1 ZINC000116020993

ZINC000116020993 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2[C@H]1CC[C@@H](OCO)CC1 ZINC000101675188

ZINC000101675188 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CCOCC3)c2=O)cn1 ZINC000117698047

ZINC000117698047 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CCC3)c2=O)cn1 ZINC000084689720

ZINC000084689720 (search)

Cc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(=O)C(C)(C)O)CC2)c(=O)n4C)cn1 ZINC000095592906

ZINC000095592906 (search)

COc1cccc2c1nc(C(F)F)n2-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073160257

ZINC000073160257 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@H]3CC[C@@H](OCO)CC3)c2=O)cn1 ZINC000261187578

ZINC000261187578 (search)

Nc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073138395

ZINC000073138395 (search)

COc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)cc(N2CCOCC2)n1 ZINC000073139306

ZINC000073139306 (search)

COc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C)CC2)c(=O)n4C)cn1 ZINC000095591885

ZINC000095591885 (search)

Cc1nc(N)nc2c1cc(-c1cnc3ccccc3c1)c(=O)n2[C@H]1CC[C@@H](OCC(N)=O)CC1 ZINC000101675235

ZINC000101675235 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2[C@H]1CC[C@@H](OCC(N)=O)CC1 ZINC000101675241

ZINC000101675241 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n([C@@H]3CCOC3)c2=O)cn1 ZINC000142932978

ZINC000142932978 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2[C@H]1CC[C@H](OCC(N)=O)CC1 ZINC000101675218

ZINC000101675218 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C1CCC1 ZINC000084687563

ZINC000084687563 (search)

Cc1nc(N)nc2c1cc(-c1cnc3ccccc3c1)c(=O)n2[C@H]1CC[C@H](OCC(N)=O)CC1 ZINC000101675208

ZINC000101675208 (search)

COc1cc(N(C)C)cc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073157897

ZINC000073157897 (search)

Cc1nc(N)nc2c1cc(-c1cnc3ccccc3c1)c(=O)n2[C@H]1CC[C@@H](OCO)CC1 ZINC000101675285

ZINC000101675285 (search)

FC(F)c1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000001912926

ZINC000001912926 (search)

COC(=O)c1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073138404

ZINC000073138404 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n(N3CCCC3)c2=O)cn1 ZINC000084671628

ZINC000084671628 (search)

Cc1nc(N)nc2c1cc(-c1cnn(C)c1)c(=O)n2[C@H]1CC[C@@H](OCO)CC1 ZINC000101675290

ZINC000101675290 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2N1CCCC1 ZINC000084671627

ZINC000084671627 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2[C@H]1CC[C@H](OCO)CC1 ZINC000101675271

ZINC000101675271 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C(C)C ZINC000084672152

ZINC000084672152 (search)

CCCOc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141609

ZINC000073141609 (search)

Cc1nc(N)nc2c1cc(-c1cnn(C)c1)c(=O)n2[C@H]1CC[C@@H](OCC(N)=O)CC1 ZINC000101675237

ZINC000101675237 (search)

Cc1nc(N)nc2c1cc(-c1cnc3ccccc3c1)c(=O)n2[C@H]1CC[C@H](OCO)CC1 ZINC000101675261

ZINC000101675261 (search)

Cc1nc(N)nc2c1cc(-c1cnn(C)c1)c(=O)n2[C@H]1CC[C@H](OCC(N)=O)CC1 ZINC000101675213

ZINC000101675213 (search)

COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CC3)c2=O)cn1 ZINC000084672151

ZINC000084672151 (search)

FC(F)Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141614

ZINC000073141614 (search)

Cc1nc(N)nc2c1cc(-c1cnn(C)c1)c(=O)n2[C@H]1CC[C@H](OCO)CC1 ZINC000101675266

ZINC000101675266 (search)

OCc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073138401

ZINC000073138401 (search)

CCCCOc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141612

ZINC000073141612 (search)

FC(F)c1nc2ccccc2n1-c1nc(N2CCOCC2)cc(N2CCOCC2)n1 ZINC000073160090

ZINC000073160090 (search)

COc1c(O)ccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073156458

ZINC000073156458 (search)

FCc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073140974

ZINC000073140974 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C1CC1 ZINC000084690567

ZINC000084690567 (search)

COc1ccc2c(nc(C(F)F)n2-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)c1O ZINC000073167155

ZINC000073167155 (search)

COc1cc(OC)c2nc(C(F)F)n(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)c2c1 ZINC000073156463

ZINC000073156463 (search)

N#Cc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141683

ZINC000073141683 (search)

FC(F)c1nc2ccccc2n1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073160255

ZINC000073160255 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3CCC[C@@H]3c3ccccc3)n2)c2c(N)ncnc21 ZINC000073221753

ZINC000073221753 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3CCN(C=O)[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000082157797

ZINC000082157797 (search)

CCN(CC)n1c(=O)c(-c2cn[nH]c2)cc2c(C)nc(N)nc21 ZINC000084688122

ZINC000084688122 (search)

Cc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073140972

ZINC000073140972 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3CCN[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000073222431

ZINC000073222431 (search)

CSCc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141303

ZINC000073141303 (search)

FC(F)(F)c1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073140977

ZINC000073140977 (search)

CS(=O)(=O)c1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141312

ZINC000073141312 (search)

CNc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073138398

ZINC000073138398 (search)

CC(C)n1cc(C(=O)c2cncc(NCCc3cccnc3)n2)c2c(N)ncnc21 ZINC000073221751

ZINC000073221751 (search)

c1ccc2c(c1)ncn2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073140968

ZINC000073140968 (search)

CS(=O)(=O)Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073138393

ZINC000073138393 (search)

CNC(=O)c1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073129306

ZINC000073129306 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3CCC[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000073223436

ZINC000073223436 (search)

COc1ccc2c(nc(C(F)F)n2-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)c1OC ZINC000073141689

ZINC000073141689 (search)

CC(C)Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141616

ZINC000073141616 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3CNC[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000073222429

ZINC000073222429 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3CCO[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000073222427

ZINC000073222427 (search)

CS(=O)(=O)Cc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141306

ZINC000073141306 (search)

O=c1cc(N2CCOCC2)oc2c(-c3ccccc3)cccc12 ZINC000000006014

ZINC000000006014 (search)

FC(F)c1nc2c3c(ccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1)OCO3 ZINC000073141686

ZINC000073141686 (search)

CC(C)n1cc(C(=O)c2cncc(N[C@@H]3COC[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000073223440

ZINC000073223440 (search)

C[S@@+]([O-])Cc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073326631

ZINC000073326631 (search)

CC(C)n1cc(C(=O)c2cncc(N(C)[C@@H]3CCC[C@@H]3c3ccc(F)cc3)n2)c2c(N)ncnc21 ZINC000073223438

ZINC000073223438 (search)

Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2NCC(C)C ZINC000084671626

ZINC000084671626 (search)

COc1cccc(-c2nc(-c3cc4cc(OC)ccc4[nH]c3=O)no2)c1 ZINC000005248543

ZINC000005248543 (search)

COc1cncc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073160089

ZINC000073160089 (search)

CC(=O)N1CC[C@@H](Nc2cncc(C(=O)c3cn(C(C)C)c4ncnc(N)c34)n2)[C@H]1c1ccc(F)cc1 ZINC000073219542

ZINC000073219542 (search)

CC(=O)N1CC[C@@H](Nc2cncc(C(=O)c3cn(C(C)C)c4ncnc(N)c34)n2)[C@H]1c1ccccc1 ZINC000073219547

ZINC000073219547 (search)

COc1cccc(CSc2nnc(-c3ccc(C)cc3O)o2)c1 ZINC000084616644

ZINC000084616644 (search)

CSc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073141309

ZINC000073141309 (search)

O=c1oc2cc(O)ccc2cc1-c1nc2ccccc2s1 ZINC000000146104

ZINC000000146104 (search)

CN(C)c1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 ZINC000073138399

ZINC000073138399 (search)