PLK2

Reference Set (104 Compounds)

CC[C@@H]1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 ZINC000013986815

ZINC000013986815 (search)

CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccncc4)cc3)n2)c(=O)c1=O ZINC000101595683

ZINC000101595683 (search)

Cc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049072889

ZINC000049072889 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 ZINC000042201314

ZINC000042201314 (search)

CNc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049073264

ZINC000049073264 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3N)ncc1CC2 ZINC000049125762

ZINC000049125762 (search)

CSc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049113125

ZINC000049113125 (search)

C[C@@H](Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1OC(F)F ZINC000043066194

ZINC000043066194 (search)

COc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049070510

ZINC000049070510 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3F)ncc1CC2 ZINC000049784613

ZINC000049784613 (search)

COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC ZINC000006745792

ZINC000006745792 (search)

COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000053276122

ZINC000053276122 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3C(F)(F)F)ncc1CC2 ZINC000049783714

ZINC000049783714 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)N5CCNCC5)CC4)ccc3OC(F)(F)F)ncc1CC2 ZINC000064528326

ZINC000064528326 (search)

CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 ZINC000003814434

ZINC000003814434 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3OC(F)(F)F)ncc1CC2 ZINC000064512419

ZINC000064512419 (search)

COc1ccc(N2CCN(C)CC2)cc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049113058

ZINC000049113058 (search)

CC(=O)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049112872

ZINC000049112872 (search)

C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O ZINC000003781738

ZINC000003781738 (search)

C=Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 ZINC000043196883

ZINC000043196883 (search)

CN1CCC[C@H]1CCNc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2c(c(C(N)=O)nn2C)CC3)c1 ZINC000064526298

ZINC000064526298 (search)

C[C@@H](Oc1cc(-n2cnc3ccc(CN4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F ZINC000043154472

ZINC000043154472 (search)

CC(C)c1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049112289

ZINC000049112289 (search)

CN1CCN(c2ccc3nc(-c4c(N)c5c(F)cccc5[nH]c4=O)[nH]c3c2)CC1 ZINC000003816310

ZINC000003816310 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N[C@@H]4CCCN4)ccc3OC(F)(F)F)ncc1CC2 ZINC000071317845

ZINC000071317845 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N[C@@H]4CCNC4)ccc3OC(F)(F)F)ncc1CC2 ZINC000064513650

ZINC000064513650 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)OC(C)(C)C)CC4)ccc3OC(F)(F)F)ncc1CC2 ZINC000064528325

ZINC000064528325 (search)

COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl ZINC000022448983

ZINC000022448983 (search)

COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 ZINC000055760827

ZINC000055760827 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N)ccc3OC(F)(F)F)ncc1CC2 ZINC000064526467

ZINC000064526467 (search)

CN1CCN(CCCNc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000071318348

ZINC000071318348 (search)

CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 ZINC000036056301

ZINC000036056301 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(NC(=O)[C@@H]4CCCN4)ccc3OC(F)(F)F)ncc1CC2 ZINC000071316469

ZINC000071316469 (search)

CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)[C@H](CO)C1 ZINC000071329387

ZINC000071329387 (search)

CN1CCC(C(=O)Nc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000071296682

ZINC000071296682 (search)

N#CC[C@H](C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 ZINC000043207851

ZINC000043207851 (search)

CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)N[C@H]4O ZINC000101364035

ZINC000101364035 (search)

CC(=O)Nc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 ZINC000049784253

ZINC000049784253 (search)

CN1CC=C(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000071296607

ZINC000071296607 (search)

Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 ZINC000019862646

ZINC000019862646 (search)

Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3Oc3ccccc3)ncc1CC2 ZINC000049112762

ZINC000049112762 (search)

CCN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000064513639

ZINC000064513639 (search)

CN1CCC(Nc2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000064513819

ZINC000064513819 (search)

CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000043196882

ZINC000043196882 (search)

CN(C)CCCN1CCC(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 ZINC000071317162

ZINC000071317162 (search)

$CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C ZINC000003964325$

ZINC000003964325 (search)

$Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1 ZINC000003938668$

ZINC000003938668 (search)

Cn1c(=O)c(Sc2ccc(F)cc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 ZINC000206664755

ZINC000206664755 (search)

CN[C@H]1C[C@H]2O[C@@H]([C@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 ZINC001772640402

ZINC001772640402 (search)

CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)nc2N1C1CCCC1 ZINC000043205414

ZINC000043205414 (search)

C[C@H](Nc1cc2c(-c3ccc4c(c3)OCO4)noc2cn1)c1ccccc1 ZINC000040424450

ZINC000040424450 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1C1CCCC1 ZINC000095921024

ZINC000095921024 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccn(C)n1 ZINC000096272670

ZINC000096272670 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1[C@H]1CCOC1 ZINC000096272674

ZINC000096272674 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1cc[nH]n1 ZINC000096272657

ZINC000096272657 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1CCC(F)(F)F ZINC000096272678

ZINC000096272678 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1C1CC(F)(F)C1 ZINC000096272646

ZINC000096272646 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1cn[nH]c1 ZINC000096272647

ZINC000096272647 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1[C@@H]1CCC(F)(F)C1 ZINC000096272675

ZINC000096272675 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccc(F)cc1 ZINC000096272663

ZINC000096272663 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1c1ccccc1 ZINC000096272661

ZINC000096272661 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1cnn(C)c1 ZINC000096272659

ZINC000096272659 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1[C@@H]1CCOC1 ZINC000096272673

ZINC000096272673 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1C(C)C ZINC000096272672

ZINC000096272672 (search)

CC[C@]1(C)C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1CCC(F)(F)F ZINC000096272650

ZINC000096272650 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccc(C#N)cc1 ZINC000096272652

ZINC000096272652 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1[C@H]1CCOC1 ZINC000096272649

ZINC000096272649 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1C1CCOCC1 ZINC000096272677

ZINC000096272677 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1[C@H]1CCOC1 ZINC000096272669

ZINC000096272669 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1CCC(F)(F)F ZINC000096272654

ZINC000096272654 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1c1cncnc1 ZINC000096272648

ZINC000096272648 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1C(C)C ZINC000096272641

ZINC000096272641 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1c1cn[nH]c1 ZINC000096272660

ZINC000096272660 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3ccc(F)cc3F)nc2N1c1cnn(C)c1 ZINC000096272671

ZINC000096272671 (search)

CN1C(=O)[C@@H](CC(F)(F)F)N(CCC(F)(F)F)c2nc(-n3ccnc3-c3ccc(F)cc3)ncc21 ZINC000096272655

ZINC000096272655 (search)

CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O ZINC000150542774

ZINC000150542774 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3nccs3)nc2N1c1cnn(C)c1 ZINC000096272667

ZINC000096272667 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-c3cn[nH]c3-c3ccccn3)nc2N1c1cnn(C)c1 ZINC000096272665

ZINC000096272665 (search)

C[C@H](Nc1cc2c(-c3cc(Cl)cc(CCC(N)=O)c3)noc2cn1)c1ccccc1 ZINC000040951123

ZINC000040951123 (search)

CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccc(CCOCc2ccccc2)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O ZINC001772654119

ZINC001772654119 (search)

CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1c(F)cccc1Oc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O ZINC001772654826

ZINC001772654826 (search)

CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1ccc(CCO)cc1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O ZINC001772583400

ZINC001772583400 (search)

Cn1c(=O)c(S(=O)(=O)c2ccc(F)cc2F)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 ZINC000117727769

ZINC000117727769 (search)

COc1ccc(S(=O)(=O)c2cc3cnc(Nc4ccc5[nH]ccc5c4)nc3n(C)c2=O)cc1 ZINC000198723227

ZINC000198723227 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccc4ccccc43)nc2N1C1CCCC1 ZINC000117883576

ZINC000117883576 (search)

Cn1c(=O)c(S(=O)(=O)c2ccc(O)cc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 ZINC000198725367

ZINC000198725367 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccnn1C ZINC000096272644

ZINC000096272644 (search)

CC[C@@H]1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1C1COC1 ZINC000096272642

ZINC000096272642 (search)

Cn1c(=O)c(S(=O)(=O)c2ccc(F)cc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 ZINC000198737751

ZINC000198737751 (search)

CC(C)N1c2nc(-n3ccnc3-c3ccc(F)cc3)ncc2N(C)C(=O)C12CCC2 ZINC000096272645

ZINC000096272645 (search)

Cn1c(=O)c(S(=O)(=O)c2ccccc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 ZINC000117717848

ZINC000117717848 (search)

Cc1cccc(-c2noc3cnc(N[C@@H](C)c4ccccc4)cc23)c1 ZINC000040951784

ZINC000040951784 (search)

$COc1ccc(Br)cc1/C=c1\sc2nc(=O)c(C)nn2c1=O ZINC000001134893$

ZINC000001134893 (search)

O=C1Nc2ccccc2/C1=C/c1ccc2[nH]ncc2c1 ZINC000096273709

ZINC000096273709 (search)

CC(C)N1c2nc(-n3ccnc3-c3ccc(F)cc3)ncc2N(C)C(=O)C1(C)C ZINC000096272643

ZINC000096272643 (search)

CC(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cncn1CCCCCCCCc1c(F)cccc1Oc1cccc(O)c1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(N)=O)[C@@H](C)OP(=O)(O)O ZINC001772590762

ZINC001772590762 (search)

$O=C1Nc2ccc(F)cc2/C1=C\c1ccc2cn[nH]c2c1 ZINC000096273711$

ZINC000096273711 (search)

$O=C1Nc2ccccc2/C1=C\c1ccc2cn[nH]c2c1 ZINC000096273692$

ZINC000096273692 (search)

Cn1c(=O)c(S(=O)(=O)c2ccc(F)cc2)cc2cnc(Nc3cccc4[nH]ccc34)nc21 ZINC000198737731

ZINC000198737731 (search)

$O=C1Nc2ccccc2/C1=C\c1ccc2n[nH]nc2c1 ZINC000096273710$

ZINC000096273710 (search)

NS(=O)(=O)c1cccc(-c2n[nH]c3ccc(NC(=O)[C@@H](c4ccsc4)N4CCCC4)cc23)c1 ZINC000072317673

ZINC000072317673 (search)

$CC(=O)Nc1ccc2c(c1)/C(=C\c1ccc3cn[nH]c3c1)C(=O)N2 ZINC000096273705$

ZINC000096273705 (search)

$COc1ccc2c(c1)/C(=C\c1ccc3cn[nH]c3c1)C(=O)N2 ZINC000096273713$

ZINC000096273713 (search)

CC(=O)Nc1ccc2c(c1)NC(=O)/C2=C/c1ccc2cn[nH]c2c1 ZINC000101690201

ZINC000101690201 (search)