HIV-1 protease

Reference Set (44 Compounds)

O=C(N[C@H]1c2ccccc2C[C@H]1O)[C@H](Cc1ccccc1)CC(O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O ZINC000003915219

ZINC000003915219 (search)

CC(C)(C)NC(=O)[C@@H]1CN(Cc2cccnc2)CCN1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O ZINC000022448696

ZINC000022448696 (search)

Cc1ccc(C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cn1 ZINC000137663712

ZINC000137663712 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NCc1ccccn1)S(=O)(=O)c1ccc(N)cc1 ZINC000138192610

ZINC000138192610 (search)

COC(=O)N[C@@H](CC1CCCCC1)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000138679425

ZINC000138679425 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](CC1CCCCC1)NC(=O)c1cccnc1)S(=O)(=O)c1ccc(N)cc1 ZINC000138714779

ZINC000138714779 (search)

Cc1ccc(C(=O)N[C@@H](Cc2ccccc2C)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1O ZINC000138755486

ZINC000138755486 (search)

COC(=O)N[C@H](C(=O)NCCCC[C@H](C(N)=O)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)C(c1ccccc1)c1ccccc1 ZINC000138824689

ZINC000138824689 (search)

CC(=O)N[C@H](C(=O)NCCCC[C@@H](C(N)=O)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)C(c1ccccc1)c1ccccc1 ZINC000148969082

ZINC000148969082 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccccc1Cl)NC(=O)c1ccncc1)S(=O)(=O)c1ccc(N)cc1 ZINC000148972098

ZINC000148972098 (search)

Cc1ccccc1C[C@H](NC(=O)c1cccnc1)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000148972337

ZINC000148972337 (search)

Cc1ccccc1C[C@H](NC(=O)c1cccc(C)c1O)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000148972977

ZINC000148972977 (search)

O=C(O)CNC(=O)c1c(=O)oc(O)c2cc(Br)ccc12 ZINC000165945019

ZINC000165945019 (search)

C[C@H](NC(=O)c1c(=O)oc(O)c2cccc(-c3cccc(C(F)(F)F)c3)c12)C(=O)O ZINC000166111633

ZINC000166111633 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccc2ccccc2c1)NS(=O)(=O)c1ccc2c(c1)OCC[C@@H]2C)S(=O)(=O)c1ccc(N)cc1 ZINC000169702510

ZINC000169702510 (search)

CCC(=O)NC(=O)N(C)CC(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000169702512

ZINC000169702512 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](NS(=O)(=O)c1cccs1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702513

ZINC000169702513 (search)

CN[C@H](C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1)[C@@H](c1ccccc1)[C@@H]1C=CC=CC1 ZINC000169702514

ZINC000169702514 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](NC(=O)NCC1=CCCN=C1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702516

ZINC000169702516 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](NC(=O)NCc1ccncc1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702517

ZINC000169702517 (search)

COC(=O)N[C@H](C(=O)NCCCC[C@@H](CO)N(Cc1cccnc1)S(=O)(=O)c1ccc(N)cc1)C(c1ccccc1)c1ccccc1 ZINC000169702518

ZINC000169702518 (search)

CC(C)CN([C@@H](CCCCNC(=O)[C@H](CC1=C2C=CC=C[C@@H]2CC=C1)NC(=O)N1CCOCC1)C(N)=O)S(=O)(=O)c1ccc(N)cc1 ZINC000169702519

ZINC000169702519 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccccc1Br)NC(=O)c1cnccn1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702521

ZINC000169702521 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](Cc1ccccc1Br)NC(=O)c1ccccn1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702522

ZINC000169702522 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](Cc1ccccc1Br)NC(=O)c1cccnc1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702523

ZINC000169702523 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](Cc1ccccc1Br)NC(=O)c1ccc2c(c1)OCO2)S(=O)(=O)c1ccc(N)cc1 ZINC000169702524

ZINC000169702524 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](Cc1ccccc1Br)NC(=O)c1ccncc1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702525

ZINC000169702525 (search)

Cc1ncccc1C(=O)N[C@@H](Cc1ccccc1Br)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000169702527

ZINC000169702527 (search)

Cc1ccc(C(=O)N[C@@H](Cc2ccccc2Br)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cn1 ZINC000169702528

ZINC000169702528 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccccc1Br)NC(=O)C1=NC[C@@H](C)N=C1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702529

ZINC000169702529 (search)

Cc1cccnc1C(=O)N[C@@H](Cc1ccccc1Br)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000169702531

ZINC000169702531 (search)

Cc1ccc(C(=O)N[C@@H](Cc2ccccc2Br)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c2ccc(N)cc2)cc1O ZINC000169702532

ZINC000169702532 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccccc1Br)NC(=O)OCc1ccncc1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702533

ZINC000169702533 (search)

Cc1c(O)cccc1C(=O)N[C@@H](Cc1ccccc1Br)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000169702534

ZINC000169702534 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccccc1Br)NC(=O)c1cccc(=O)[nH]1)S(=O)(=O)c1ccc(N)cc1 ZINC000169702535

ZINC000169702535 (search)

CC(C)CN(Sc1ccc2c(c1)CCO2)[C@H](CO)CCCCNC(=O)[C@@H](Cc1cccc2ccccc12)NC(=O)N1CCOCC1 ZINC000169702536

ZINC000169702536 (search)

CC(C)CN(Sc1ccc2c(c1)OCCO2)[C@H](CO)CCCCNC(=O)[C@@H](Cc1cccc2ccccc12)NC(=O)N1CCOCC1 ZINC000169702537

ZINC000169702537 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](Cc1ccccc1Br)NC(=O)N1CCOCC1)S(=O)(=O)c1ccc2c(c1)CCO2 ZINC000169702538

ZINC000169702538 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@H](CC1=C(Br)CCC=C1)NC(=O)N1CCOCC1)S(=O)(=O)c1ccc2c(c1)OCCO2 ZINC000169702539

ZINC000169702539 (search)

COC(=O)N[C@H](C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc2c(c1)CCO2)[C@H](C1=CC=CCC1)c1ccccc1 ZINC000169702540

ZINC000169702540 (search)

CC(C)CN([C@H](CO)CCCCNC(=O)[C@@H](NC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1)S(=O)(=O)c1ccc2c(c1)CCO2 ZINC000169702542

ZINC000169702542 (search)

COC(=O)N[C@H](C(=O)NCCCC[C@H](CO)N(CC(C)C)S(=O)(=O)c1ccc2c(c1)N(C)CCO2)C(c1ccccc1)c1ccccc1 ZINC000169702543

ZINC000169702543 (search)

COC(=O)N[C@H](C(=O)NCCCC[C@H](CO)N(CC(C)C)S(=O)(=O)c1cccc2cccnc12)C(c1ccccc1)c1ccccc1 ZINC000169702544

ZINC000169702544 (search)

Cc1ncccc1C(=O)N[C@@H](Cc1ccccc1Cl)C(=O)NCCCC[C@@H](CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 ZINC000169702545

ZINC000169702545 (search)