RIPK2

Reference Set (69 Compounds)

COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1 ZINC000019632614

ZINC000019632614 (search)

Nc1c(-c2ccc(F)cc2)c(-c2ccncc2)nn1-c1c(Cl)cc(Cl)cc1Cl ZINC000084604180

ZINC000084604180 (search)

COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 ZINC000053683345

ZINC000053683345 (search)

CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 ZINC000002047743

ZINC000002047743 (search)

COc1cc2c(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ccnc2cc1OCCCN1CCOCC1 ZINC000043204048

ZINC000043204048 (search)

C[S@@+]([O-])c1ccc(-c2nc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)cc1 ZINC000003815700

ZINC000003815700 (search)

Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCN(CCO)CC2)n1 ZINC000003986735

ZINC000003986735 (search)

CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 ZINC000036056301

ZINC000036056301 (search)

COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1 ZINC000003948085

ZINC000003948085 (search)

COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)N[C@H](C)c1nccs1 ZINC000003819294

ZINC000003819294 (search)

CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F ZINC000039059267

ZINC000039059267 (search)

Nc1nc(N)c2nc(-c3cccc(O)c3)c(-c3cccc(O)c3)nc2n1 ZINC000006718666

ZINC000006718666 (search)

Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O ZINC000011617039

ZINC000011617039 (search)

C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O ZINC000003781738

ZINC000003781738 (search)

C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 ZINC000001546066

ZINC000001546066 (search)

C[C@@H](Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl ZINC000035902489

ZINC000035902489 (search)

Cn1c(Nc2ccc(C(F)(F)F)cc2)nc2cc(Oc3ccnc(-c4ncc(C(F)(F)F)[nH]4)c3)ccc21 ZINC000018710085

ZINC000018710085 (search)

COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC ZINC000006745792

ZINC000006745792 (search)

CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 ZINC000023247639

ZINC000023247639 (search)

CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 ZINC000001493878

ZINC000001493878 (search)

CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1 ZINC000016697102

ZINC000016697102 (search)

OCCn1cc(-c2ccc3c(c2)CC/C3=N\O)c(-c2ccncc2)n1 ZINC000100015335

ZINC000100015335 (search)

CN(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1 ZINC000003976838

ZINC000003976838 (search)

CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 ZINC000043204002

ZINC000043204002 (search)

Cc1cc2c(F)c(Oc3ncnn4cc(OC[C@@H](C)O)c(C)c34)ccc2[nH]1 ZINC000013684256

ZINC000013684256 (search)

CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1 ZINC000001550477

ZINC000001550477 (search)

COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl ZINC000022448983

ZINC000022448983 (search)

O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 ZINC000043201999

ZINC000043201999 (search)

CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 ZINC000003814434

ZINC000003814434 (search)

Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1 ZINC000024044436

ZINC000024044436 (search)

Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 ZINC000019862646

ZINC000019862646 (search)

CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc21 ZINC000018710082

ZINC000018710082 (search)

COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 ZINC000055760827

ZINC000055760827 (search)

CNC(=O)c1ccccc1Sc1ccc2c(/C=C/c3ccccn3)n[nH]c2c1 ZINC000003816287

ZINC000003816287 (search)

COc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1S(=O)(=O)C(C)(C)C ZINC000202009534

ZINC000202009534 (search)

CCOc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1S(=O)(=O)C(C)(C)C ZINC000202143704

ZINC000202143704 (search)

COCCOc1cc2nccc(Nc3[nH]nc(C)c3C)c2cc1S(=O)(=O)C(C)(C)C ZINC000147123613

ZINC000147123613 (search)

CCc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1S(=O)(=O)C(C)(C)C ZINC000202146224

ZINC000202146224 (search)

Cc1[nH]nc(Nc2ccnc3cc(OCCO)c(S(=O)(=O)C(C)(C)C)cc23)c1C ZINC000202150560

ZINC000202150560 (search)

CCOc1cc2ncc(-c3cc(N)nc(F)c3)n2cc1S(=O)(=O)C(C)(C)C ZINC000914431283

ZINC000914431283 (search)

Cc1ccc(O)cc1Nc1ccnc2ccc(S(C)(=O)=O)cc12 ZINC000001491556

ZINC000001491556 (search)

CC(C)(C)S(=O)(=O)c1ccc2nccc(Nc3n[nH]c4ccc(F)cc34)c2c1 ZINC000140121291

ZINC000140121291 (search)

Cc1[nH]nc(Nc2ccnc3ccc(S(=O)(=O)C(C)(C)C)cc23)c1C ZINC000114190184

ZINC000114190184 (search)

CS(=O)(=O)c1ccc2nccc(Nc3ccc4scnc4c3)c2c1 ZINC000140021788

ZINC000140021788 (search)

CS(=O)(=O)c1cccc(Nc2nccc(-c3sc(N4CCOCC4)nc3-c3cccc(NS(=O)(=O)c4c(F)cccc4F)c3)n2)c1 ZINC000263620900

ZINC000263620900 (search)

Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12 ZINC000036701290

ZINC000036701290 (search)

Cc1ccc(O)cc1Nc1ccnc2ccc(C(F)(F)F)cc12 ZINC000033981408

ZINC000033981408 (search)

Cc1ccc(O)cc1Nc1ccnc2ccc(-c3cccnc3)cc12 ZINC000028823955

ZINC000028823955 (search)

CC(C)S(=O)(=O)c1ccc2nccc(Nc3n[nH]c4ccc(F)cc34)c2c1 ZINC000140004931

ZINC000140004931 (search)

COCCNC(=O)c1ccc2c(c1)nc(-c1cnc(-c3ccc(Cl)cc3)[nH]1)n2CCOC ZINC000199570879

ZINC000199570879 (search)

Cc1ccc(O)cc1Nc1ccnc2ccc(C(=O)NCC3CCOCC3)cc12 ZINC000139938544

ZINC000139938544 (search)

Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(C(N)=O)cc24)CCC3)n1 ZINC000003959536

ZINC000003959536 (search)

CS(=O)(=O)c1ccc2nccc(Nc3ccc4[nH]nnc4c3)c2c1 ZINC000139679007

ZINC000139679007 (search)

CS(=O)(=O)c1ccc2nccc(Nc3n[nH]c4ccc(F)cc34)c2c1 ZINC000140098690

ZINC000140098690 (search)

Cc1cccc(-c2[nH]c(CNc3ccccc3F)nc2-c2ccc3ncnn3c2)n1 ZINC000113391423

ZINC000113391423 (search)

CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)no1 ZINC000000602848

ZINC000000602848 (search)

CC(C)(C)S(=O)(=O)c1ccc2nccc(Nc3[nH]nc4ncc(F)cc34)c2c1 ZINC000199001529

ZINC000199001529 (search)

Cc1cccc(-c2[nH]c(Cc3cccc(C(N)=O)c3)nc2-c2ccc3nccnc3c2)n1 ZINC000013985930

ZINC000013985930 (search)

COc1ccc2nccc(Nc3cc(O)ccc3C)c2c1 ZINC000653907650

ZINC000653907650 (search)

CNc1cc(Oc2c(F)cc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2F)ccn1 ZINC000653859586

ZINC000653859586 (search)

Cc1ccc(O)cc1Nc1ccnc2ccccc12 ZINC000653907626

ZINC000653907626 (search)

Cc1cccc(-c2nc(C(C)(C)C)[nH]c2-c2ccc3c(c2)OCO3)n1 ZINC000016052825

ZINC000016052825 (search)

O=C(Nc1ccccc1Cl)c1cnn2ccccc12 ZINC000005035585

ZINC000005035585 (search)

CC(C)(C)n1nc(-c2ccc(Cl)cc2)c2c(N)ncnc21 ZINC000001383151

ZINC000001383151 (search)

COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC ZINC000001386783

ZINC000001386783 (search)

Cc1ccc(-c2nn(C(C)(C)C)c3ncnc(N)c23)cc1 ZINC000002047275

ZINC000002047275 (search)

CC(C)(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc21 ZINC000002576349

ZINC000002576349 (search)

CC(C)(C)n1nc(Cc2cccc3ccccc23)c2c(N)ncnc21 ZINC000013132888

ZINC000013132888 (search)

NC(=O)c1ccc(-c2nc(-c3ccc4c(c3)OCO4)c(-c3ccccn3)[nH]2)cc1 ZINC000000603769

ZINC000000603769 (search)