TOP2A

Reference Set (89 Compounds)

NCCCNc1ccc2c3c(nn2CCNCCO)-c2c(O)ccc(O)c2C(=O)c13 ZINC000001581128

ZINC000001581128 (search)

O=C1c2c(O)cccc2-c2nn(CCNCCO)c3ccc(NCCNCCO)c1c23 ZINC000001583637

ZINC000001583637 (search)

O=C1c2cccnc2-c2nccc3c2c1nc1ccccc13 ZINC000001645485

ZINC000001645485 (search)

N[C@@H]1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c5ccc6c7ccccc7ccc6c5oc2c34)C1 ZINC000001658939

ZINC000001658939 (search)

N[C@H]1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c5ccc6c7ccccc7ccc6c5oc2c34)C1 ZINC000001658940

ZINC000001658940 (search)

Cc1c2ccncc2c(C)c2c1[nH]c1ccccc12 ZINC000001846592

ZINC000001846592 (search)

O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21 ZINC000003794794

ZINC000003794794 (search)

COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12 ZINC000003812923

ZINC000003812923 (search)

O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 ZINC000003874317

ZINC000003874317 (search)

COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 ZINC000003918087

ZINC000003918087 (search)

Clc1ccccc1/C=N/Nc1nc2ccccc2n2cnnc12 ZINC000004793395

ZINC000004793395 (search)

c1ccc2c(c1)nc(NC1CCCCC1)c1nncn12 ZINC000004910692

ZINC000004910692 (search)

c1nc2c(NC3CCCCCC3)nc(Nc3ccc4ncsc4c3)nc2[nH]1 ZINC000013985259

ZINC000013985259 (search)

CNc1nc2ccccc2n2cnnc12 ZINC000026378084

ZINC000026378084 (search)

C=C(CC[C@H](C(=O)O)[C@H]1CC[C@@]2(C)C3=CC[C@H]4C(C)(C)C(=O)CC[C@]4(C)C3=CC[C@]12C)C(C)C ZINC000028654660

ZINC000028654660 (search)

C=C(C)[C@@H]1CC[C@]2(C(=O)OC)CC[C@]3(CO)[C@H](CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12 ZINC000038943867

ZINC000038943867 (search)

CN(CCO)CCn1nc2c3c(cccc31)C(=O)c1c(Cl)cccc1-2 ZINC000040874260

ZINC000040874260 (search)

CC(C)(C)Nc1nc(Nc2ccc3ncsc3c2)nc2[nH]cnc12 ZINC000043061941

ZINC000043061941 (search)

COc1ccccc1CNCCCn1c(=O)c2ccc3c(=O)n(CCCNCc4ccccc4OC)c(=O)c4ccc(c1=O)c2c34 ZINC000049723161

ZINC000049723161 (search)

C[C@@H]1COC2=CC(=O)C(=O)c3cccc1c32 ZINC000072107234

ZINC000072107234 (search)

C=CCC1=COC2=C(Cl)C(=O)C(=O)c3cccc1c32 ZINC000072107340

ZINC000072107340 (search)

O=C1C=C2OC[C@@](O)(Cc3ccccc3)c3cccc(c32)C1=O ZINC000072108491

ZINC000072108491 (search)

CN(CCNC(=O)CCC(=O)NCCN(C)CCn1nc2c3c(cccc31)C(=O)c1c(Cl)cccc1-2)CCn1nc2c3c(cccc31)C(=O)c1c(Cl)cccc1-2 ZINC000095536808

ZINC000095536808 (search)

CN(CCOC(=O)CCCCC(=O)OCCN(C)CCn1nc2c3c(cccc31)C(=O)c1c(Cl)cccc1-2)CCn1nc2c3c(cccc31)C(=O)c1c(Cl)cccc1-2 ZINC000095540577

ZINC000095540577 (search)

CCCCNC[C@H](O)COc1cc(O)c2c(=O)c3ccccc3oc2c1 ZINC000096933354

ZINC000096933354 (search)

CCCCCc1ccc(-c2cn([C@@H]3COC4=C(Br)C(=O)C(=O)c5cccc3c54)nn2)cc1 ZINC000096934558

ZINC000096934558 (search)

N=c1c2c(=S)n(-c3ccccc3)c(=S)n(-c3ccccc3)c2nc(NCCc2ccc(Cl)cc2)n1-c1ccccc1 ZINC000103165483

ZINC000103165483 (search)

N=c1c2c(=S)n(-c3ccccc3)c(=S)n(-c3ccccc3)c2nc(NCc2cccnc2)n1-c1ccccc1 ZINC000103165485

ZINC000103165485 (search)

N=c1c2c(=S)n(-c3ccccc3)c(=S)n(-c3ccccc3)c2nc(NCCN2CCCCC2)n1-c1ccccc1 ZINC000103165492

ZINC000103165492 (search)

COC1=C(CCNC(C)=O)c2nc3ccccc3c3ccnc(c23)C1=O ZINC000103173370

ZINC000103173370 (search)

CCC(=O)NCCC1=C(SC)C(=O)c2nccc3c2c1nc1ccccc13 ZINC000103174001

ZINC000103174001 (search)

COc1cc(CCNC(=O)C=C(C)C)c2[nH]c3ccccc3c3ccnc1c23 ZINC000103174005

ZINC000103174005 (search)

C/C=C(\C)C(=O)[C@@H](CNCC(=O)O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 ZINC000103195053

ZINC000103195053 (search)

CC(C)(O)CC(=O)[C@@H](CNCC=O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 ZINC000103195057

ZINC000103195057 (search)

CC(C)=CC(=O)[C@@H](CNCC(=O)O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 ZINC000103195063

ZINC000103195063 (search)

C/C=C(\C)C(=O)[C@@H](CNCC=O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 ZINC000103195067

ZINC000103195067 (search)

CC(C)=CC(=O)[C@@H](CNCC=O)C1=CC(=O)c2nccc3c2c1nc1ccccc13 ZINC000103195075

ZINC000103195075 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)c3cccs3)c(OC)c2)ccc1OC(=O)c1cccs1 ZINC000103274846

ZINC000103274846 (search)

CCCCCCC(=O)Oc1ccc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CCCCCC)c(OC)c2)cc1OC ZINC000103276209

ZINC000103276209 (search)

CCCCCCC(=O)Oc1ccc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CCCCCC)c(OCC)c2)cc1OCC ZINC000103276211

ZINC000103276211 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNCCCl)c(OC)c2)ccc1OC(=O)CNCCCl ZINC000103276379

ZINC000103276379 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNCCCl)c(OCC)c2)ccc1OC(=O)CNCCCl ZINC000103278911

ZINC000103278911 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)c(OCC)c2)ccc1O ZINC000103279012

ZINC000103279012 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CCNCCCl)c(OC)c2)ccc1OC(=O)CCNCCCl ZINC000103280580

ZINC000103280580 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNc3ccc(S(N)(=O)=O)cc3)c(OC)c2)ccc1OC(=O)CNc1ccc(S(N)(=O)=O)cc1 ZINC000150608160

ZINC000150608160 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNCCN(CC)CC)c(OCC)c2)ccc1OC(=O)CNCCN(CC)CC ZINC000150608452

ZINC000150608452 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CCNC34CC5CC(CC(C5)C3)C4)c(OCC)c2)ccc1OC(=O)CCNC12CC3CC(CC(C3)C1)C2 ZINC000150608454

ZINC000150608454 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CCNCCN(CC)CC)c(OCC)c2)ccc1OC(=O)CCNCCN(CC)CC ZINC000150608465

ZINC000150608465 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)C34CC5CC(CC(C5)C3)C4)c(OC)c2)ccc1OC(=O)C12CC3CC(CC(C3)C1)C2 ZINC000150608490

ZINC000150608490 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CN(CCCl)CCCl)c(OC)c2)ccc1OC(=O)CN(CCCl)CCCl ZINC000150608557

ZINC000150608557 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CN(CCCl)CCCl)c(OCC)c2)ccc1OC(=O)CN(CCCl)CCCl ZINC000150608859

ZINC000150608859 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNC34CC5CC(CC(C5)C3)C4)c(OC)c2)ccc1OC(=O)CNC12CC3CC(CC(C3)C1)C2 ZINC000150608868

ZINC000150608868 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNC34CC5CC(CC(C5)C3)C4)c(OCC)c2)ccc1OC(=O)CNC12CC3CC(CC(C3)C1)C2 ZINC000150609108

ZINC000150609108 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNc3nnc(C)s3)c(OCC)c2)ccc1OC(=O)CNc1nnc(C)s1 ZINC000150609114

ZINC000150609114 (search)

CCOc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNCCN(C)C)c(OCC)c2)ccc1OC(=O)CNCCN(C)C ZINC000150609134

ZINC000150609134 (search)

CCN(CC)CCNCC(=O)Oc1ccc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CNCCN(CC)CC)c(OC)c2)cc1OC ZINC000150609474

ZINC000150609474 (search)

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(OC(=O)CCNc3nnc(C)s3)c(OC)c2)ccc1OC(=O)CCNc1nnc(C)s1 ZINC000150609499

ZINC000150609499 (search)

C=C1NC(=O)[C@H](C)[C@H](CC[C@H](C)C(=O)/C=C/C(C)=C/C[C@H](C)CCCCCCC)OC(=O)[C@H](C[C@@H](OS(=O)(=O)O)C(N)=O)NC(=O)[C@@H](C)CNC1=O ZINC000195281498

ZINC000195281498 (search)

O=c1c2ccc(Cl)cc2sc2c(N3CCNCC3)nc3ccccc3c12 ZINC000473166245

ZINC000473166245 (search)

CN(C)CCCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc(C#N)c(C#N)nc21 ZINC000653687131

ZINC000653687131 (search)

Cc1c2cn(C)ccc2cc2c1c1ccccc1[n+]2C ZINC000653723625

ZINC000653723625 (search)

N[C@H]1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c5ccc([N+](=O)[O-])cc5oc2c34)C1 ZINC001772570854

ZINC001772570854 (search)

O=C1C(=O)C([C@H](c2ccc(Br)cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772570907

ZINC001772570907 (search)

O=C1C(=O)C([C@H](c2ccc(Cl)cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772572052

ZINC001772572052 (search)

COc1ccccc1CNCCCn1c(=O)c2ccc3c(=O)n(CCCNCCCN)c(=O)c4ccc(c1=O)c2c34 ZINC001772576590

ZINC001772576590 (search)

O=C(Nc1ccccc1)c1c(O)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O ZINC001772576816

ZINC001772576816 (search)

NCCCCNCCCNC[C@H](O)COc1cc(O)c2c(=O)c3ccccc3oc2c1 ZINC001772578640

ZINC001772578640 (search)

CN(C)CCOc1ccc2ccc3c4c(nnc3c2c1)-c1ccccc1C4=O ZINC001772579727

ZINC001772579727 (search)

NCCCNCCCCNCCCNC[C@H](O)COc1cc(O)c2c(=O)c3ccccc3oc2c1 ZINC001772582693

ZINC001772582693 (search)

Nc1ccc2c(c1)oc1c(N3CCNCC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 ZINC001772605017

ZINC001772605017 (search)

O=C1C(=O)C([C@H](c2ccccc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772605602

ZINC001772605602 (search)

CN(C)CCCCNC(=O)c1ccc2nnc3c(c2c1)C(=O)c1ccccc1-3 ZINC001772610420

ZINC001772610420 (search)

Nc1ccc2c(c1)oc1c(NCCN3CCOCC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 ZINC001772611756

ZINC001772611756 (search)

NCCCNC[C@@H](O)COc1cc(O)c2c(=O)c3ccccc3oc2c1 ZINC001772614577

ZINC001772614577 (search)

O=C1C(=O)C([C@H](c2ccc([N+](=O)[O-])cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772614837

ZINC001772614837 (search)

Nc1ccc2c(c1)oc1c(N3CCC(N4CCCCC4)CC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 ZINC001772616697

ZINC001772616697 (search)

COc1ccccc1CNCCCn1c(=O)c2ccc3c(=O)n(CCCCNCCCN)c(=O)c4ccc(c1=O)c2c34 ZINC001772618058

ZINC001772618058 (search)

COc1ccccc1CNCCCn1c(=O)c2ccc3c(=O)n(CCCNCCCCNCCCN)c(=O)c4ccc(c1=O)c2c34 ZINC001772623971

ZINC001772623971 (search)

O=C1C(=O)C([C@H](c2ccc3c(c2)OCO3)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772627502

ZINC001772627502 (search)

NCCCCNC[C@@H](O)COc1cc(O)c2c(=O)c3ccccc3oc2c1 ZINC001772630263

ZINC001772630263 (search)

CN(C)CCCCNc1nc2ccccc2c2nc3ccccc3nc12 ZINC001772633551

ZINC001772633551 (search)

COc1ccccc1CNCCCn1c(=O)c2ccc3c(=O)n(CCCOCCCCOCCCN)c(=O)c4ccc(c1=O)c2c34 ZINC001772636880

ZINC001772636880 (search)

COc1ccccc1CNCCCn1c(=O)c2ccc3c(=O)n(CCCNCCCCN)c(=O)c4ccc(c1=O)c2c34 ZINC001772641011

ZINC001772641011 (search)

CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c5ccc(N)cc5oc2c34)CC1 ZINC001772642688

ZINC001772642688 (search)

O=C1C(=O)C([C@H](c2ccc(F)cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772644416

ZINC001772644416 (search)

O=C1C(=O)C([C@H](c2ccccc2F)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc21 ZINC001772644657

ZINC001772644657 (search)

Nc1ccc2c(c1)oc1c(N3CC[C@H](N)C3)c(F)cc3c(=O)c(C(=O)O)cn2c13 ZINC001772650265

ZINC001772650265 (search)

CN(C)CCCNC(=O)c1ccc2nnc3c(c2c1)C(=O)c1ccccc1-3 ZINC001772652581

ZINC001772652581 (search)

Nc1ccc2c(c1)oc1c(N3CC[C@@H](N)C3)c(F)cc3c(=O)c(C(=O)O)cn2c13 ZINC001772658146

ZINC001772658146 (search)