Results of Job: search_95bb4172-0312-4203-abd3-614fc695b353

Query Target Key Target Name Description P-Value MaxTC

compound_1

DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 7.686e-71 0.46
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 3.488e-50 0.48
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 5.838e-49 0.62
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 3.737e-47 0.38
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.635e-37 0.39
CP125_MYCTU cyp125 Steroid C26-monooxygenase 8.861e-35 0.43
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 4.491e-34 0.45
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 1.017e-33 0.42
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 9.803e-30 0.36
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 3.081e-26 0.32
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 1.856e-24 0.39
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 2.728e-24 0.30
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 1.72e-21 0.36
SHBG_HUMAN SHBG Sex hormone-binding globulin 8.255e-21 0.38
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 1.126e-18 0.30
FGF2_HUMAN FGF2 Fibroblast growth factor 2 2.422e-18 0.40
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 2.016e-17 0.48
NR1H4_HUMAN NR1H4 Bile acid receptor 2.328e-17 0.36
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 1.11e-16 0.31
RORA_HUMAN RORA Nuclear receptor ROR-alpha 2.22e-16 0.62
ABCBB_HUMAN ABCB11 Bile salt export pump 9.167e-13 0.31
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 5.22e-11 0.36
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 5.99e-11 0.36
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 2.505e-10 0.52
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 2.161e-09 0.39
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 6.147e-09 0.30
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 7.504e-09 0.42
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.386e-08 0.36
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 2.633e-08 0.51
CAH4_BOVIN CA4 Carbonic anhydrase 4 6.975e-08 0.30
ESR2_HUMAN ESR2 Estrogen receptor beta 2.316e-07 0.36
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 2.741e-07 0.34
ANDR_HUMAN AR Androgen receptor 8.597e-07 0.36
NR1H4_MOUSE Nr1h4 Bile acid receptor 1.227e-06 0.32
DPOLB_RAT Polb DNA polymerase beta 1.869e-06 0.31